Ophthalmic Pathology Laboratory, University of Toronto, St. Michael's Hospital, Li Ka Shing Knowledge Institute, Toronto, ON, Canada.
J Glaucoma. 2013 Jun-Jul;22 Suppl 5:S24-5. doi: 10.1097/IJG.0b013e3182934a55.
Many glaucoma patients continue to lose vision despite treatment to lower intraocular pressure. In addition to the loss of retinal ganglion cells in the eye, there is injury to major visual pathways of the brain along the retino-geniculo-cortical pathway. Evidence for this comes from both glaucoma models and glaucoma patients. Understanding central visual system changes in glaucoma will provide insights into human glaucomatous neural degeneration and disease progression, in addition to potential novel strategies to prevent vision loss in glaucoma.
尽管降低眼内压的治疗可以控制眼压，但许多青光眼患者的视力仍在继续下降。除了眼睛中的视网膜神经节细胞损失外，沿着视网膜-膝状体-皮质通路的大脑主要视觉通路也受到了损伤。这一证据来自于青光眼模型和青光眼患者。了解青光眼患者的中枢视觉系统变化，除了为预防青光眼患者的视力丧失提供新的策略外，还可以深入了解人类青光眼神经退行性变和疾病进展。
