Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland.
Chembiochem. 2013 Jul 8;14(10):1185-7. doi: 10.1002/cbic.201300248. Epub 2013 Jun 3.
A ringing belt: An artificial molecular machine was invented to build up a programmable peptidic sequence. By molecular movements, the rotaxane-based machine progressively introduces amino acids to form a short peptide chain. The journey towards an artificial ribosome is still quite long, but a conceivable future can be envisaged.
发明了一种人工分子机器来构建可编程的肽序列。通过分子运动,轮烷基机器逐步引入氨基酸形成短肽链。迈向人工核糖体的旅程还相当漫长,但可以想象未来的情景。