巴雷特食管的警示性成像技术。

Red flag imaging techniques in Barrett's esophagus.

作者信息

Saxena Payal, Canto Marcia Irene

机构信息

Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins Medical Institutions, 1830 East Monument Street, Baltimore, MD 21287, USA.

出版信息

Gastrointest Endosc Clin N Am. 2013 Jul;23(3):535-47. doi: 10.1016/j.giec.2013.03.002. Epub 2013 May 3.

DOI:10.1016/j.giec.2013.03.002

PMID:23735101

Abstract

The key to detection and treatment of early neoplasia in Barrett's esophagus (BE) is thorough and careful inspection of the Barrett's segment. The greatest role for red flag techniques is to help identify neoplastic lesions for targeted biopsy and therapy. High-definition white light endoscopy (HD-WLE) can potentially improve endoscopic imaging of BE compared with standard endoscopy, but little scientific evidence supports this. The addition of autofluorescence imaging to HD-WLE and narrow band imaging increases sensitivity and the false-positive rate without significantly improving overall detection of BE-related neoplasia.

摘要

巴雷特食管（BE）早期肿瘤形成的检测与治疗关键在于对巴雷特段进行全面且仔细的检查。警示技术的最大作用是帮助识别肿瘤性病变以便进行靶向活检和治疗。与标准内镜检查相比，高清白光内镜检查（HD-WLE）可能会改善BE的内镜成像，但几乎没有科学证据支持这一点。在HD-WLE基础上增加自体荧光成像和窄带成像虽可提高敏感性和假阳性率，但并未显著改善BE相关肿瘤形成的总体检测情况。