魁北克慢性肝病决定因素的演变
Evolution of the determinants of chronic liver disease in Quebec.
作者信息
Sanabria A J, Dion R, Lúcar E, Soto J C
机构信息
Direction des risques biologiques et de la santé au travail, Institut national de santé publique du Québec, Montréal, Quebec, Canada.
出版信息
Chronic Dis Inj Can. 2013 Jun;33(3):137-45.
INTRODUCTION
Chronic liver diseases (CLDs) are a worldwide problem. Morbidity and mortality due to CLDs could be avoided or reduced by targeting the main risk factors, including obesity and alcohol use.
METHODS
To describe the evolution of the key determinants of CLDs in Quebec, we studied the trends in obesity, alcohol use, viral hepatitis B and C, CLD mortality and hospitalization rates, and the liver cancer incidence rate between January 1, 1981, and December 31, 2009.
RESULTS
We observed an increase in the obesity indicators among young men and in alcohol use among adolescent girls and middle-aged women. The overall hepatitis B and C incidence and CLD mortality rates are falling. However, liver cancer and mortality rates, especially among men and the elderly, are on the rise.
CONCLUSION
These results highlight the importance of targeted public health interventions and of maintaining or improving access to care for CLDs.
引言
慢性肝病是一个全球性问题。通过针对包括肥胖和饮酒在内的主要风险因素，可以避免或降低慢性肝病导致的发病率和死亡率。
方法
为描述魁北克慢性肝病关键决定因素的演变，我们研究了1981年1月1日至2009年12月31日期间肥胖、饮酒、乙型和丙型病毒性肝炎、慢性肝病死亡率和住院率以及肝癌发病率的趋势。
结果
我们观察到年轻男性肥胖指标上升，青春期女孩和中年女性饮酒量增加。乙型和丙型肝炎总体发病率以及慢性肝病死亡率正在下降。然而，肝癌发病率和死亡率，尤其是男性和老年人中的发病率和死亡率正在上升。
结论
这些结果凸显了有针对性的公共卫生干预措施以及维持或改善慢性肝病医疗服务可及性的重要性。
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