Ballard J E, McKeown B C, Graham H M, Zinkgraf S A
University of Texas, Tyler 75701.
Int J Sports Med. 1990 Jun;11(3):208-14. doi: 10.1055/s-2007-1024793.
The purpose of this study was to assess the effect of physical activity (PA) and estrogen therapy (ET) upon bone mass at the 1/3 and 4 mm distal radial sites in 50 postmenopausal females. The Ss (means age = 57.4 +/- 5.4 yrs) completed: 1) activity and gynecological surveys, 2) Balke treadmill tests (85% of age determined HR), and 3) single photon absorptiometry measurements of the radius. The activity surveys and treadmill tests were used to categorize Ss into high (8.5 METs or greater, n = 27) and low (6.0 METs or less, n = 23) physical activity groups (HPA/LPA), and the gynecological surveys were used to distinguish Ss who were on estrogen therapy (n = 17) and those who had never been on estrogen therapy (n = 33). Data revealed the HPA group had significantly higher BMC (g/cm) and BMC/BW (g/cm2) at the 1/3 distal radial site than the LPA group (.834 g/cm to .721 g/cm, p less than .01; and .698 g/cm2 to .653 g/cm2, p less than .06, respectively) but were not significantly different at the 4 mm distal site. The ET group had a significantly higher bone mass than the never on ET group for BMC/BW at the 4 mm site (.907 g/cm to .809 g/cm p less than .027). It was concluded that high level physical activity (8.5 METs or greater) or estrogen therapy was helpful in reducing the risk of bone loss in postmenopausal women.
本研究旨在评估体育活动（PA）和雌激素疗法（ET）对50名绝经后女性桡骨远端1/3处和4毫米处骨量的影响。受试者（平均年龄=57.4±5.4岁）完成了：1）活动和妇科调查；2）巴尔克跑步机测试（达到年龄相关心率的85%）；3）桡骨单光子吸收测量。活动调查和跑步机测试用于将受试者分为高体力活动组（8.5梅脱或更高，n=27）和低体力活动组（6.0梅脱或更低，n=23）（HPA/LPA），妇科调查用于区分接受雌激素治疗的受试者（n=17）和从未接受过雌激素治疗的受试者（n=33）。数据显示，HPA组桡骨远端1/3处的骨矿含量（BMC，克/厘米）和BMC/体重（克/厘米²）显著高于LPA组（分别为0.834克/厘米对0.721克/厘米，p<0.01；以及0.698克/厘米²对0.653克/厘米²，p<0.06），但在4毫米远端处无显著差异。ET组在4毫米处的BMC/体重骨量显著高于未接受ET组（0.907克/厘米对0.809克/厘米，p<0.027）。研究得出结论，高水平体育活动（8.5梅脱或更高）或雌激素疗法有助于降低绝经后女性骨质流失的风险。
