Kempf H G
Universitäts-HNO-Klinik Tübingen.
HNO. 1990 May;38(5):166-9.
Since 1969 we have seen 17 patients with non-Hodgkin's lymphoma of the parotid gland. Retrospective analysis of these patients reveals that the primary diagnosis was established in 14 patients by parotid surgery. In 10 (58.8%) cases there was a single focus of NHL in the parotid gland proven by extensive medical and radiological examinations. Histology showed that 14 (82.3%) of the tumors were low grade and 3 (17.7%) were high grade (Kiel classification). In 5 specimens myoepithelial sialadenitis was found in the parotid gland tissue. Six patients died within 1.5 years on average, 4 of them without evidence of disease. Four of the 7 patients alive have been followed for an average of 3.1 years without evidence of disease. Primary radiation of the parotid region in stage IE in cases of parotid gland NHL seems to be an effective therapy. NHL presenting in myoepithelial sialadenitis seems to be rare, but offers the opportunity of observing an organ specific malignant process.
自1969年以来，我们共诊治了17例腮腺非霍奇金淋巴瘤患者。对这些患者的回顾性分析显示，14例患者通过腮腺手术得以确立初步诊断。在10例（58.8%）病例中，经全面的医学检查和影像学检查证实腮腺内存在单个非霍奇金淋巴瘤病灶。组织学检查表明，14例（82.3%）肿瘤为低级别，3例（17.7%）为高级别（ Kiel分类法）。在5份标本中，腮腺组织内发现了肌上皮涎腺炎。6例患者平均在1.5年内死亡，其中4例无疾病证据。7例存活患者中有4例平均随访3.1年，无疾病证据。腮腺非霍奇金淋巴瘤IE期患者对腮腺区域进行原发放疗似乎是一种有效的治疗方法。肌上皮涎腺炎中出现的非霍奇金淋巴瘤似乎很罕见，但提供了观察器官特异性恶性过程的机会。
