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Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes.活性氧水平通过低剂量地拉罗司控制低危骨髓增生异常综合征红系祖细胞中NF-κB的激活。
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Long-term hematological response in a patient with 5q- syndrome after suspension of lenalidomide therapy and further improvement with deferasirox therapy.来那度胺治疗中断后5q-综合征患者的长期血液学反应及地拉罗司治疗后的进一步改善
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Iron chelation therapy with deferasirox in the management of iron overload in primary myelofibrosis.用地拉罗司进行铁螯合疗法治疗原发性骨髓纤维化中的铁过载
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本文引用的文献

1
An update on iron chelation therapy.铁螯合疗法的最新进展。
Blood Transfus. 2012 Oct;10(4):411-22. doi: 10.2450/2012.0008-12. Epub 2012 Jun 27.
2
Deferasirox treatment for myelodysplastic syndromes: "real-life" efficacy and safety in a single-institution patient population.地拉罗司治疗骨髓增生异常综合征:单中心患者人群中的“真实世界”疗效和安全性。
Ann Hematol. 2012 Sep;91(9):1345-9. doi: 10.1007/s00277-012-1481-7. Epub 2012 May 9.
3
Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes.去铁斯若治疗依赖输血的骨髓增生异常综合征患者的血液学反应
Haematologica. 2012 Sep;97(9):1364-71. doi: 10.3324/haematol.2011.048546. Epub 2012 Mar 14.
4
Positive effects on hematopoiesis in patients with myelodysplastic syndrome receiving deferasirox as oral iron chelation therapy: a brief review.地拉罗司治疗骨髓增生异常综合征患者的造血作用:简要综述。
Leuk Res. 2011 May;35(5):566-70. doi: 10.1016/j.leukres.2010.11.027. Epub 2010 Dec 23.
5
Deferasirox treatment interruption in a transfusion-requiring myelodysplastic patient led to loss of erythroid response.一名需要输血的骨髓增生异常综合征患者中断地拉罗司治疗导致红系反应丧失。
Acta Haematol. 2010;124(1):46-8. doi: 10.1159/000314961. Epub 2010 Jul 9.

Haematological improvement as a beneficial effect during deferasirox treatment in transfusion-dependent patients with myelodysplastic syndrome.

作者信息

Molica Matteo, Salaroli Adriano, Alimena Giuliana, Breccia Massimo

机构信息

Department of Cellular Biotechnologies and Haematology, Sapienza University, Rome, Italy.

出版信息

Blood Transfus. 2014 Jan;12 Suppl 1(Suppl 1):s162-3. doi: 10.2450/2013.0005-13. Epub 2013 Apr 15.

DOI:10.2450/2013.0005-13
PMID:23736908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3934268/
Abstract
摘要