偶然发现的小肾癌延迟手术后的临床结果。
Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery.
机构信息
Department of Urology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan ; Department of Urology, Sakai Hospital Kinki University Faculty of Medicine, Sakai, Osaka, Japan.
出版信息
Cancer Manag Res. 2013 May 24;5:85-9. doi: 10.2147/CMAR.S44221. Print 2013.
BACKGROUND
This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery.
METHODS
We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during surveillance from January 2000 to December 2011. Radiographic evaluations using computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed at least every 6 months, and the tumor size was determined at least twice.
RESULTS
The mean follow-up time was 26.6 ± 18.6 months and mean tumor doubling time was 23.4 ± 16.0 months. Histopathological analysis revealed that 32 of the 34 patients were malignant in pT1aN0M0. Only one patient showed tumor recurrence, who subsequently died due to tumor progression.
CONCLUSION
The growth rate of the small renal mass was slow in the majority of our patients. Delayed intervention does not have a detrimental effect on cancer-specific outcomes.
背景
本研究旨在探讨小肾肿瘤（SRM）患者延迟手术后的生长速度和临床结局。
方法
我们回顾了 2000 年 1 月至 2011 年 12 月期间接受监测的 34 例诊断时肿瘤直径≤4cm 的 SRM 患者的临床记录，这些患者在监测期间接受了延迟手术干预。使用计算机断层扫描（CT）和磁共振成像（MRI）进行影像学评估，至少每 6 个月进行一次，至少两次确定肿瘤大小。
结果
平均随访时间为 26.6±18.6 个月，平均肿瘤倍增时间为 23.4±16.0 个月。组织病理学分析显示，34 例患者中有 32 例为 pT1aN0M0 期恶性肿瘤。只有 1 例患者出现肿瘤复发，随后因肿瘤进展而死亡。
结论
我们的大多数患者的小肾肿瘤生长速度较慢。延迟干预对癌症特异性结局没有不利影响。
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