Chiu Tin Lok, Sadler Lynn, Wise Michelle R
National Women's Hospital, Auckland, New Zealand.
Aust N Z J Obstet Gynaecol. 2013 Oct;53(5):455-8. doi: 10.1111/ajo.12098. Epub 2013 Jun 6.
To identify additional risk factors for placenta praevia in women with prior caesarean section.
A retrospective case-control study of 53 cases and 157 controls was performed. Information was obtained from the National Women's database between 2004 and 2009. Cases were defined as women with diagnosed placenta praevia over 20 weeks' gestation and having had one or more prior caesarean sections. Risk factors assessed from the prior caesarean section were (i) type of suture used for hysterotomy closure; (ii) stage of labour; (iii) type of primary surgeon; and (iv) model of funding. Univariate and logistical regression analyses were performed.
Use of monofilament suture for hysterotomy closure in prior caesarean section significantly reduced the chance of having placenta praevia in the index pregnancy (adjusted odds ratio 0.26, 95% confidence interval 0.08-0.80), as did prior caesarean being performed in the first stage of labour (aOR 0.36, 95% CI 0.14-0.92). Type of primary surgeon (specialist vs trainee junior doctor), nor model of funding of prior caesarean section (public vs private), was associated with risk of placenta praevia (privately funded specialist aOR 4.75, 95% CI 0.89-25.23 and trainee junior doctor aOR 3.18, 95% CI 0.59-17.28, respectively).
A prior caesarean section performed in first stage, and monofilament suture for hysterotomy closure, reduced the chance of having placenta praevia in the index pregnancy.
确定既往有剖宫产史的女性前置胎盘的其他危险因素。
进行了一项回顾性病例对照研究,纳入53例病例和157例对照。信息取自2004年至2009年的国家妇女数据库。病例定义为妊娠20周以上诊断为前置胎盘且有一次或多次既往剖宫产史的女性。从既往剖宫产中评估的危险因素包括:(i)子宫切口缝合所用缝线类型;(ii)产程阶段;(iii)主刀医生类型;(iv)资助模式。进行了单因素和逻辑回归分析。
既往剖宫产子宫切口缝合使用单丝缝线显著降低了本次妊娠发生前置胎盘的几率(调整比值比0.26,95%置信区间0.08 - 0.80),既往剖宫产在产程第一阶段进行也有同样效果(调整比值比0.36,95%置信区间0.14 - 0.92)。主刀医生类型(专科医生与实习初级医生)以及既往剖宫产的资助模式(公立与私立)均与前置胎盘风险无关(私立资助的专科医生调整比值比4.75,95%置信区间0.89 - 25.23;实习初级医生调整比值比3.18,95%置信区间0.59 - 17.28)。
既往剖宫产在第一阶段进行以及子宫切口缝合使用单丝缝线可降低本次妊娠发生前置胎盘的几率。