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产妇发病率与选择性剖宫产产妇前置胎盘相关。

Maternal morbidity associated with placenta praevia among women who had elective caesarean section.

机构信息

Office for Clinical Research and Audit, Royal College of Obstetricians and Gynaecologists, London, UK.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2011 Nov;159(1):62-6. doi: 10.1016/j.ejogrb.2011.07.008. Epub 2011 Aug 10.

DOI:10.1016/j.ejogrb.2011.07.008
PMID:21835537
Abstract

OBJECTIVE

Estimates of the increased risk of maternal complications after caesarean section posed by placenta praevia differ between studies and may not reflect current practice. We assess the impact of placenta praevia on maternal complications after elective caesarean section (CS).

STUDY DESIGN

We undertook a retrospective cohort study of women who had an elective CS for a singleton at term in the English National Health Service between 1 April 2000 and 28 February 2009 using routine data from the Hospital Episode Statistics database. Multiple logistic regression was used to estimate the effect of placenta praevia on maternal complications after controlling for maternal age, parity, whether a woman had a previous CS, and gestational age. Maternal complications included postpartum haemorrhage, obstetric trauma, blood transfusion and hysterectomy.

RESULTS

Among 131,731 women having an elective CS for a singleton, 4,332 (3.3%) women had placenta praevia. Placenta praevia increased the risk of postpartum haemorrhage from 9.7% to 17.5% (adjusted odds ratio (OR) 1.91; 95% CI: 1.74 to 2.09), the risk of blood transfusion from 1.4% to 6.4% (OR 4.39; 3.76 to 5.12), and the risk of hysterectomy from 0.03% to 1% (OR 39.70; 22.42 to 70.30). Previous studies have estimated the rate of hysterectomy among women with placenta praevia to be 5%.

CONCLUSION

Placenta praevia remains a risk factor for various maternal complications, although the increased risk of hysterectomy is lower than previously reported.

摘要

目的

剖宫产术后前置胎盘导致母体并发症风险增加的估计值在不同研究中存在差异,并且可能无法反映当前的实践情况。我们评估了前置胎盘对择期剖宫产(CS)后母体并发症的影响。

研究设计

我们使用来自医院事件统计数据库的常规数据,对 2000 年 4 月 1 日至 2009 年 2 月 28 日期间在英国国家卫生服务机构中因单胎足月行择期 CS 的妇女进行了回顾性队列研究。使用多因素逻辑回归来估计在控制了母亲年龄、产次、是否有既往剖宫产史和孕龄后,前置胎盘对母亲并发症的影响。母体并发症包括产后出血、产科创伤、输血和子宫切除术。

结果

在 131731 名因单胎足月行择期 CS 的妇女中,有 4332 名(3.3%)妇女患有前置胎盘。前置胎盘使产后出血的风险从 9.7%增加到 17.5%(调整后的优势比(OR)1.91;95%置信区间(CI):1.74 至 2.09),输血的风险从 1.4%增加到 6.4%(OR 4.39;3.76 至 5.12),子宫切除术的风险从 0.03%增加到 1%(OR 39.70;22.42 至 70.30)。之前的研究估计前置胎盘妇女子宫切除术的发生率为 5%。

结论

前置胎盘仍然是各种母体并发症的危险因素,尽管子宫切除术的风险增加幅度低于之前的报告。

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