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台湾地区住院酒精使用障碍患者童年期逆境与自杀未遂的关联。

Association between childhood adversities and suicide attempts among alcoholic inpatients in Taiwan.

机构信息

Taipei City Psychiatric Center, Xinyi District, Taipei, 110 Taiwan.

出版信息

J Stud Alcohol Drugs. 2013 Jul;74(4):559-64. doi: 10.15288/jsad.2013.74.559.

DOI:10.15288/jsad.2013.74.559
PMID:23739019
Abstract

OBJECTIVE

Alcohol dependence is frequently associated with suicide attempts. A history of adverse childhood experiences (ACEs) increases the risk of emotional and behavioral problems in adulthood. Child abuse is reported to increase suicide risk among alcohol-dependent patients. However, other types of ACEs, including ACEs related to family dysfunction that may have exceptional impact among the Chinese, are rarely explored.

METHOD

The contribution of a broad spectrum of ACEs to lifetime risk of suicide attempts among alcoholic inpatients in Taiwan was examined. Family Health History Questionnaires were used to assess ACEs among 194 male alcohol-dependent inpatients admitted for alcohol detoxification. Logistic regression analysis was applied to examine the prediction of ACEs for lifetime risk of suicide attempts.

RESULTS

The rate of attempted suicide in this cohort was 27.4%. The prevalence of ACEs was high, with around 90% of participants reporting at least one type of ACE. In the regression analysis, after adjusting for lifetime depression, illicit drug use, and severity of alcohol dependence, having had a battered mother (odds ratio [OR] = 3.99, 95% CI [1.40, 11.34]) and having parents who were separated/divorced (OR = 7.35, 95% CI [1.56, 34.72]) were associated with the risk of suicide attempts, but having experienced physical and sexual abuse were not. A 1-unit increase in childhood adversity raised the likelihood of a suicide attempt by 61% (OR = 1.61, 95% CI [1.16, 2.25]).

CONCLUSIONS

There is a direct and graded relationship between childhood adversities and lifetime risk of suicide attempts among male alcoholic patients. In Chinese societies, adversities related to parental separation, divorce, and interparental violence may have a specific effect in aggravating suicide risk.

摘要

目的

酒精依赖常与自杀未遂相关。不良的童年经历(ACEs)增加了成年后患情绪和行为问题的风险。据报道,虐待儿童会增加酒精依赖患者的自杀风险。然而,其他类型的 ACEs,包括可能对中国人有特殊影响的与家庭功能障碍相关的 ACEs,很少被探索。

方法

本研究考察了广泛的 ACEs 对台湾酒精住院患者一生中自杀未遂风险的贡献。使用家庭健康史问卷评估了 194 名男性酒精依赖住院患者的 ACEs,这些患者因酒精解毒而入院。应用逻辑回归分析检验 ACEs 对一生中自杀未遂风险的预测作用。

结果

该队列的自杀未遂率为 27.4%。ACEs 的发生率很高,约 90%的参与者报告至少有一种 ACEs。在回归分析中,在校正了一生中的抑郁、非法药物使用和酒精依赖的严重程度后,有被殴打母亲(比值比[OR] = 3.99,95%置信区间[1.40, 11.34])和父母离异(OR = 7.35,95%置信区间[1.56, 34.72])与自杀未遂的风险相关,但经历过身体和性虐待则没有。儿童逆境增加一个单位,自杀未遂的可能性增加 61%(OR = 1.61,95%置信区间[1.16, 2.25])。

结论

在男性酒精患者中,儿童期逆境与一生中自杀未遂的风险之间存在直接的、分级的关系。在华人社会中,与父母离异、离婚以及父母间暴力相关的逆境可能具有特殊的加重自杀风险的作用。

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