Almeida Rui M S, Leitão Luciano
Institute of Cardiovascular Surgery of Paraná, Cascavel, Paraná, Brazil.
Rev Bras Cir Cardiovasc. 2013 Mar;28(1):76-82. doi: 10.5935/1678-9741.20130012.
The use of cell saver (CS) in cardiac surgery is proposed to reduce the use of units of packed red blood cells stored (URBC), which increases morbidity, mortality and causes inflammatory reactions.
The objective is to evaluate whether the use of CS decreases the use URBC, is cost /effective and beneficial to the patient.
In a prospective study, between November 2009 and October 2011, 100 consecutive patients who underwent cardiovascular surgery with CPB, hemodilution and hemofiltration, were enrolled. Patients were divided into group 1 (no CS) and 2 (CS). The criteria for the replacement of RBC were hemodynamic instability and hemoglobin (Hb) <7-8g/dl. Demographic data, as well as Hb and hematocrit, mediastinal drainage, number of URBC and CPB, ICU and hospital time, were analysed.
In groups 1 and 2 the average age was 64.1 and 60.6 years; predominantly male; the logistic EuroSCORE 10.3 and 9.4; mortality 2% and 4%. Group 2 had a higher incidence of reoperations (12% versus 6%), but the average of URBC used (4.31 versus 1.25) and mean length of hospital stay (10.8 versus 7.4 days) was lower. Univariate and multivariate analysis, were performed, which showed no statistically significant values, except in the use of URBC. The relationship between the CS and the cost of RBC was not cost /effective and length of stay was shorter.
The use of CS decreases the number of used URBC, is not cost /effective but has shown benefits for patients.
心脏手术中使用血液回收机(CS)旨在减少库存红细胞输注单位(URBC)的使用,因为URBC的使用会增加发病率、死亡率并引发炎症反应。
评估使用CS是否能减少URBC的使用、是否具有成本效益以及对患者是否有益。
在一项前瞻性研究中,于2009年11月至2011年10月期间,纳入了100例接受体外循环、血液稀释和血液滤过的心血管手术的连续患者。患者被分为1组(不使用CS)和2组(使用CS)。红细胞替代的标准是血流动力学不稳定和血红蛋白(Hb)<7 - 8g/dl。分析了人口统计学数据,以及Hb、血细胞比容、纵隔引流、URBC数量、体外循环时间、重症监护病房(ICU)时间和住院时间。
1组和2组的平均年龄分别为64.1岁和60.6岁;以男性为主;欧洲心脏手术风险评估系统(EuroSCORE)分值分别为10.3和9.4;死亡率分别为2%和4%。2组再次手术的发生率较高(12%对6%),但使用的URBC平均值(4.31对1.25)和平均住院时间(10.8天对7.4天)较低。进行了单因素和多因素分析,结果显示除URBC的使用外,其他均无统计学显著差异。CS与红细胞成本之间的关系不具有成本效益,且住院时间较短。
使用CS可减少URBC的使用数量,虽不具有成本效益,但已显示对患者有益。