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自体输血在双瓣置换术中的成功案例:保留患者自主性,获得极佳临床效果。

Successful Case of Double Valve Replacement Surgery Using Autologous Blood Transfusion: A Patient's Autonomy Preserved with Excellent Clinical Outcome.

机构信息

Department of Morphophysiology, Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.

Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

出版信息

Am J Case Rep. 2024 Jul 24;25:e943675. doi: 10.12659/AJCR.943675.

DOI:10.12659/AJCR.943675
PMID:39046936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11299883/
Abstract

BACKGROUND A blood cell saver, or autotransfusion system, is used to collect, wash, and return autologous blood collected from the surgical patient. This report describes a 55-year-old man who underwent combined mitral and aortic valve replacement surgery with cardiopulmonary bypass and had a successful outcome following intraoperative and postoperative autologous blood transfusion using a blood cell saver. CASE REPORT The patient did not accept blood transfusion for reasons of religious conscience and was in a critical condition, receiving palliative care. He needed combined mitral and aortic valve replacement surgery. The surgery was conducted using a cell saver (Sorin Xtra Autotransfusion System) in the intraoperative and postoperative periods for 24 h, to resolve this challenging case, from a technical and ethical point of view. The volume of red blood cells recovered intraoperatively was 1430 mL, with a hematocrit level of 40%, and 690 mL, with a hematocrit of 35%, in the postoperative period. Therefore, a significant volume of autologous blood was recovered. The autologous blood transfusion resulted in an excellent clinical outcome for the patient, who was discharged on the ninth postoperative day. CONCLUSIONS We can conclude that the use of a blood cell saver in cardiac surgery, in both intra- and postoperative periods, resulted in the maintenance of adequate hemoglobin and hematocrit levels, no infection postoperatively, and rapid and complete recovery of the patient. Thus, the use of the blood cell saver guaranteed the individual's autonomy to refuse blood products safely, with good clinical results, and without dependence on allogeneic blood transfusions.

摘要

背景

血液回收机,也称为自体输血系统,用于收集、清洗并回输从手术患者采集的自体血液。本报告介绍了一位 55 岁男性患者,他在体外循环下行二尖瓣和主动脉瓣联合置换术,术中及术后使用血液回收机进行自体输血,结果良好。

病例报告

患者出于宗教信仰原因拒绝输血,且病情危急,正在接受姑息治疗。他需要行二尖瓣和主动脉瓣联合置换术。该手术在术中及术后 24 小时内使用细胞保存器(Sorin Xtra 自体输血系统)进行,从技术和伦理的角度解决了这一具有挑战性的病例。术中回收的红细胞量为 1430 毫升,红细胞压积为 40%,术后为 690 毫升,红细胞压积为 35%,因此大量回收了自体血。自体输血使患者的临床状况得到了显著改善,他在术后第 9 天出院。

结论

我们可以得出结论,在心脏手术中,无论是术中还是术后,使用血液回收机可维持血红蛋白和红细胞压积水平充足,术后无感染,患者快速完全康复。因此,使用血液回收机能保证患者安全拒绝血液制品的自主权,获得良好的临床效果,且无需依赖异体输血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/47f6bcac2d46/amjcaserep-25-e943675-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/ee21808f6a9b/amjcaserep-25-e943675-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/5555e666d4fe/amjcaserep-25-e943675-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/b1bfeaf08e55/amjcaserep-25-e943675-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/098bc34d9b5c/amjcaserep-25-e943675-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/47f6bcac2d46/amjcaserep-25-e943675-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/ee21808f6a9b/amjcaserep-25-e943675-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/5555e666d4fe/amjcaserep-25-e943675-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/b1bfeaf08e55/amjcaserep-25-e943675-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/098bc34d9b5c/amjcaserep-25-e943675-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d9b/11299883/47f6bcac2d46/amjcaserep-25-e943675-g005.jpg

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Int J Surg. 2024 Jun 1;110(6):3392-3400. doi: 10.1097/JS9.0000000000001458.
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[Bacterial contamination of autologous blood in reinfusion in neurosurgery: a phenomenon or a problem?].[神经外科自体血回输中的细菌污染:一种现象还是一个问题?]
Zh Vopr Neirokhir Im N N Burdenko. 2024;88(2):54-61. doi: 10.17116/neiro20248802154.
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Autologous cell salvage in off-pump coronary artery bypass surgery reduces post-operative complications: a retrospective weighted-matching analysis.
非体外循环冠状动脉旁路移植术中使用自体细胞回收减少术后并发症:回顾性加权匹配分析。
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Perioperative Care in Cardiac Surgery: A Joint Consensus Statement by the Enhanced Recovery After Surgery (ERAS) Cardiac Society, ERAS International Society, and The Society of Thoracic Surgeons (STS).心脏外科手术的围手术期护理:增强术后恢复协会(ERAS)心脏学会、ERAS 国际学会和胸外科医师学会(STS)的联合共识声明。
Ann Thorac Surg. 2024 Apr;117(4):669-689. doi: 10.1016/j.athoracsur.2023.12.006. Epub 2024 Jan 28.
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