Geriatric Department, University Hospital of Tours, 2 Bd Tonnellé, Tours Cedex, France.
Aging Clin Exp Res. 2013 Apr;25(1):111-3. doi: 10.1007/s40520-013-0009-x. Epub 2013 Mar 27.
Levetiracetam is frequently used in the elderly considering its favorable pharmacological profile, efficacy, and good tolerance. We reported an encephalopathy with levetiracetam in an elderly subject who had no renal failure, no concomitant valproate medication, and no other additional co-morbidities. Levetiracetam should be discontinued when this condition is suspected.
左乙拉西坦因其良好的药理学特性、疗效和良好的耐受性,常用于老年人。我们报告了一例老年患者出现左乙拉西坦相关脑病,该患者无肾衰竭,无同时使用丙戊酸钠,也无其他合并症。当怀疑出现这种情况时,应停用左乙拉西坦。