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预防复吸的神经动力学:针对门诊酒驾罪犯的神经营养方法。

Neurodynamics of relapse prevention: a neuronutrient approach to outpatient DUI offenders.

作者信息

Brown R J, Blum K, Trachtenberg M C

机构信息

Cambridge Institute, San Francisco, California.

出版信息

J Psychoactive Drugs. 1990 Apr-Jun;22(2):173-87. doi: 10.1080/02791072.1990.10472542.

Abstract

The central nervous system rewarding properties of ethanol, cocaine, and heroin may activate a common catecholaminergic reward system in the mesolimbic circuitry of the brain. Driving-under-the-influence (DUI) offenders with either alcohol- or cocaine-related problems were studied. The neuronutrients SAAVE and Tropamine significantly reduced relapse rates and enhanced recovery in these DUI outpatient offenders over a 10-week period. Follow-up on both the SAAVE and Tropamine groups after 10 months revealed a 73% and a 53% overall recovery rate, respectively. These clinical results favor the use of these neuronutrients as adjuncts to psychological therapeutic modalities.

摘要

乙醇、可卡因和海洛因的中枢神经系统奖赏特性可能会激活大脑中脑边缘回路中一个共同的儿茶酚胺能奖赏系统。对有酒精或可卡因相关问题的酒后驾车(DUI)罪犯进行了研究。神经营养素SAAVE和托哌敏在10周的时间里显著降低了这些DUI门诊罪犯的复发率并促进了康复。10个月后对SAAVE组和托哌敏组的随访显示,总体康复率分别为73%和53%。这些临床结果支持将这些神经营养素用作心理治疗方式的辅助手段。

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