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应用抗糖肽脂核心抗原 IgA 抗体对鸟分枝杆菌复合群和脓肿分枝杆菌复合群肺病进行血清学诊断。

Serodiagnosis of Mycobacterium avium complex and Mycobacterium abscessus complex pulmonary disease by use of IgA antibodies to glycopeptidolipid core antigen.

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

出版信息

J Clin Microbiol. 2013 Aug;51(8):2747-9. doi: 10.1128/JCM.00702-13. Epub 2013 Jun 5.

Abstract

An enzyme immunoassay kit that detects serum IgA antibody reacting to glycopeptidolipid core antigen derived from Mycobacterium avium complex (MAC) was not useful for differentiating MAC pulmonary disease (PD) from Mycobacterium abscessus complex PD (MAB-PD). However, this assay could be useful for differentiating MAC- and MAB-PD from pulmonary tuberculosis. (This study has been registered at ClinicalTrials.gov under registration no. NCT00970801.).

摘要

一种酶免疫试剂盒,可检测血清 IgA 抗体与分支杆菌复合群(MAC)来源的糖脂核心抗原反应,对于区分 MAC 肺病(PD)和脓肿分枝杆菌复合群 PD(MAB-PD)没有帮助。然而,该检测对于区分 MAC 和 MAB-PD 与肺结核可能有用。(本研究已在 ClinicalTrials.gov 注册,注册号为 NCT00970801。)

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