Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Sendai, 980-8578, Japan.
Angew Chem Int Ed Engl. 2013 Jul 15;52(29):7536-9. doi: 10.1002/anie.201302751. Epub 2013 Jun 5.
Three-step cascade: Oxazepine derivatives were efficiently prepared from O-propargylic oximes and dipolarophiles through copper-catalyzed cascade reactions which proceed through a 2,3-rearrangement, [3+2] cycloaddition, and subsequent 1,3-oxygen rearrangement. The process involves the cleavage of C- and N-O bonds.
通过铜催化的级联反应，从 O-炔丙基肟和偶极子高效制备了噁嗪衍生物，该反应经过 2,3-重排、[3+2]环加成和随后的 1,3-氧重排。该过程涉及 C-和 N-O 键的断裂。
