结合癌胚抗原和对胃肠道肿瘤细胞具有细胞毒性的蓖麻毒素A链的双特异性抗体。 - Suppr

Suppr

超能文献

Bispecific antibody that binds carcinoembryonic antigen and ricin toxin A chain cytotoxic for gastrointestinal tract tumor cells.

作者信息

Robins R A, Embleton M J, Pimm M V, Betts D S, Charleston A, Markham A J, Baldwin R W

出版信息

J Natl Cancer Inst. 1990 Aug 1;82(15):1295-6. doi: 10.1093/jnci/82.15.1295.

DOI:10.1093/jnci/82.15.1295

PMID:2374178

Abstract

摘要

相似文献

Bispecific antibody that binds carcinoembryonic antigen and ricin toxin A chain cytotoxic for gastrointestinal tract tumor cells.结合癌胚抗原和对胃肠道肿瘤细胞具有细胞毒性的蓖麻毒素A链的双特异性抗体。

J Natl Cancer Inst. 1990 Aug 1;82(15):1295-6. doi: 10.1093/jnci/82.15.1295.

Selective cytotoxicity of a ricin A-chain-anti-carcinoembryonic antigen antibody conjugate for a human colon adenocarcinoma cell line.蓖麻毒素A链-抗癌胚抗原抗体偶联物对人结肠腺癌细胞系的选择性细胞毒性

J Natl Cancer Inst. 1982 Oct;69(4):799-805.

Recombinant ricin toxin A chain cytotoxicity against carcinoembryonic antigen expressing tumour cells mediated by a bispecific monoclonal antibody and its potentiation by ricin toxin B chain.双特异性单克隆抗体介导的重组蓖麻毒素A链对表达癌胚抗原的肿瘤细胞的细胞毒性及其受蓖麻毒素B链的增强作用

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The preparation and cytotoxic properties of antibody-toxin conjugates.抗体-毒素偶联物的制备及其细胞毒性特性

Immunol Rev. 1982;62:119-58. doi: 10.1111/j.1600-065x.1982.tb00392.x.

Capture of recombinant ricin A chain by a bispecific anti-RTA:anti-CEA monoclonal antibody pre-targeted to a human gastric carcinoma xenograft in nude mice.双特异性抗蓖麻毒素A链：抗癌胚抗原单克隆抗体预先靶向裸鼠人胃癌异种移植瘤对重组蓖麻毒素A链的捕获

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Neoplastic B cells as targets for antibody-ricin A chain immunotoxins.作为抗体重链免疫毒素靶点的肿瘤性B细胞

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Effect of a monoclonal anti-carcinoembryonic antigen antibody-ricin A-chain conjugate on human carcinoembryonic antigen-producing tumor cells.一种单克隆抗癌胚抗原抗体-蓖麻毒素A链缀合物对人癌胚抗原产生肿瘤细胞的作用。

J Pharmacobiodyn. 1984 Aug;7(8):593-603. doi: 10.1248/bpb1978.7.593.

The presence of anti-carcinoembryonic antigen (CEA) antibodies in the sera of patients with gastrointestinal malignancies.胃肠道恶性肿瘤患者血清中抗癌胚抗原（CEA）抗体的存在。

J Clin Immunol. 1994 Sep;14(5):310-3. doi: 10.1007/BF01540984.

Radioimmunodetection of gastrointestinal neoplasms with antibodies to carcinoembryonic antigen.用癌胚抗原抗体对胃肠道肿瘤进行放射免疫检测。

Cancer Res. 1980 Aug;40(8 Pt 2):2993-6.

[Cytotoxic properties of an immunotoxin interacting with mouse myeloma cells].[一种与小鼠骨髓瘤细胞相互作用的免疫毒素的细胞毒性特性]

Dokl Akad Nauk SSSR. 1984;277(3):756-9.

引用本文的文献

The influence of anti-(ricin toxin A chain) monoclonal antibodies on the pharmacokinetics of ricin toxin A chain and recombinant ricin A chain in mice.抗（蓖麻毒素A链）单克隆抗体对蓖麻毒素A链及重组蓖麻毒素A链在小鼠体内药代动力学的影响。

Cancer Immunol Immunother. 1990;32(4):235-40. doi: 10.1007/BF01741706.

Strategies in antibody therapy of cancer.癌症抗体治疗策略。

Clin Exp Immunol. 1990 Nov;82(2):189-93. doi: 10.1111/j.1365-2249.1990.tb05425.x.

J Cancer Res Clin Oncol. 1992;118(5):367-70. doi: 10.1007/BF01294441.

Targeted kill: from umbrellas to monoclonal antibodies.

J Clin Immunol. 1992 Nov;12(6):391-405. doi: 10.1007/BF00918851.

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