Demetter P, D'Haene N, Verset L, Nagy N
Department of Pathology, Erasme University Hospital, Université Libre de Bruxelles (ULB), Belgium.
Acta Chir Belg. 2013 Mar-Apr;113(2):71-6.
In Belgium, approximately 1100 new cases of pancreatic ductal adenocarcinoma are diagnosed each year. Although in the last twenty years several advances have been registered in the field of pancreatic pathology, few therapies are efficacious, and it remains one of the deadliest of all cancers. Histological variants with a somewhat different prognosis have been recognised, and precursor lesions identified. This article reviews the histological aspects of ductal adenocarcinoma, its variants and the precursor lesions. Study and knowledge of these precursor lesions offers the best hope for treating pancreatic cancer before an incurable invasive tumour develops.
在比利时，每年约有1100例新诊断的胰腺导管腺癌病例。尽管在过去二十年中胰腺病理学领域取得了一些进展，但有效的治疗方法仍然很少，它仍然是所有癌症中最致命的癌症之一。已经认识到预后略有不同的组织学变体，并确定了前驱病变。本文综述了导管腺癌的组织学方面、其变体和前驱病变。对这些前驱病变的研究和了解为在不可治愈的浸润性肿瘤发展之前治疗胰腺癌提供了最大的希望。
