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[居住在美国的日本成年人的皮肤微生物学特征]

[Cutaneous microbiologic profiles of Japanese adults residing in the United States of America].

作者信息

Nishijima S, McGinley K J, Leyden J J

机构信息

Department of Dermatology, Duhring Laboratories, University of Pennsylvania.

出版信息

Nihon Hifuka Gakkai Zasshi. 1990 Feb;100(2):175-83.

PMID:2374306
Abstract

Quantitative cutaneous bacteriological profile analysis was performed on 20 healthy Japanese adults. Five ecologically different sites were cultured, the forehead, anterior nares, axilla, perineum, and fourth interspace. Antibiotic sensitivity patterns were determined for the various species of coagulase negative cocci (CNS). Aerobic organisms were found in densities exceeding 10(6) per sample for all sites except the forehead (10(4)), while anaerobic Propionibacteria were found in quantities ranging from 10(5) to 10(6) per sample except for the toe web space, which was devoid of anaerobic organisms. CNS were ubiquitous. Staphylococcus aureus varied from 15% to 35%. Lipophilic diphtheroids were found in 50% of the subjects on the forehead and nearly 100% on other sites, whereas multiple antibiotic resistant lipophilic diphtheroids (Group JK) were found in the perineum of 35% and in the toe space of 15%. Gram negative bacilli were uncommon on the forehead, axilla, and the toe web space, but were found in 50% or more in the anterior nares and perineum. Penicillin and ampicillin resistant CNS were commonly seen, while oxacillin and cephalosporin resistance were uncommon. Tetracycline and erythromycin resistance was seen in 35% to 40%.

摘要

对20名健康的日本成年人进行了定量皮肤细菌学特征分析。培养了五个生态不同的部位,即前额、前鼻孔、腋窝、会阴和第四间隙。确定了各种凝固酶阴性球菌(CNS)的抗生素敏感性模式。除前额(10⁴)外,所有部位的需氧菌密度均超过每样本10⁶,而除趾间空间(该部位无厌氧菌)外,厌氧丙酸杆菌的数量范围为每样本10⁵至10⁶。CNS普遍存在。金黄色葡萄球菌的比例在15%至35%之间。在前额,50%的受试者发现有亲脂性类白喉杆菌,在其他部位近100%发现有亲脂性类白喉杆菌,而在35%的会阴和15%的趾间空间发现有多药耐药亲脂性类白喉杆菌(JK组)。革兰氏阴性杆菌在前额、腋窝和趾间空间不常见,但在前鼻孔和会阴中50%或更多的样本中发现。常见青霉素和氨苄青霉素耐药的CNS,而苯唑西林和头孢菌素耐药则不常见。四环素和红霉素耐药率为35%至40%。

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