Aly R, Maibach H I, Shinefield H R
Arch Dermatol. 1977 Jun;113(6):780-2.
The microbial flora of dermatitic skin, uninvolved skin, and the anterior nares of subjects with atopic eczema were investigated. The carriage rate of Staphylococcus aureus was 79% for the anterior nares, 76% for the uninvolved skin (normal skin), and 93% for lesions. The counts of S aureus were 7.5 X 10(4)/sq cm in lesions and 7.1 X 10(3)/sq cm on adjacent normal skin. Staphylococcus aureus was the predominant organism in the lesions and constituted 91% of the total aerobic bacterial flora. The coagulase-negative staphylococci were the second predominant organisms (9%). On normal skin, coagulase-negative staphylococci were the predominant organisms, constituting 63% of the total flora, followed by S aureus (30% of the bacterial flora). The micrococci counts were lower in the lesions (1.6 X 10(2)/sq cm) and higher on normal skin (9.5 X 10(2)/sq cm). Lipophilic diphtheroids were fewer on normal skin (6.7 X 10/sq cm), and there were none in the lesions. Fifty-eight percent of the strains belonged to group 3, and 38% were nontypeable. Staphylococcus aureus strains belonging to phage groups 2 and 4 were not detected.
对特应性湿疹患者的皮炎皮肤、未受累皮肤及前鼻孔的微生物菌群进行了研究。金黄色葡萄球菌在前鼻孔的携带率为79%，在未受累皮肤（正常皮肤）为76%，在皮损处为93%。皮损处金黄色葡萄球菌计数为7.5×10⁴/平方厘米，相邻正常皮肤为7.1×10³/平方厘米。金黄色葡萄球菌是皮损中的主要微生物，占需氧菌总菌群的91%。凝固酶阴性葡萄球菌是第二主要微生物（9%）。在正常皮肤上，凝固酶阴性葡萄球菌是主要微生物，占总菌群的63%，其次是金黄色葡萄球菌（占细菌菌群的30%）。微球菌计数在皮损处较低（1.6×10²/平方厘米），在正常皮肤上较高（9.5×10²/平方厘米）。亲脂性类白喉杆菌在正常皮肤上较少（6.7×10/平方厘米），在皮损中无。58%的菌株属于3组，38%不可分型。未检测到属于噬菌体2组和4组的金黄色葡萄球菌菌株。
