Davydov M I, Ryndin V D, Tuleuov A E, Akbarov A N, Mikhina Z P
Khirurgiia (Mosk). 1990 Apr(4):32-5.
The authors analyse 37-year experience in the treatment of patients with esophageal carcinoma by various methods at the All-Union Cancer Research Center. The immediate and long-term results of radiotherapy and surgical and combined treatment of 1,850 patients are shown. Bearing in mind the considerable extension of the neoplastic process by the time of the operation, the authors substantiate the expediency of one-stage operations with the formation of intrapleural esophagogastric anastomoses. The mortality in the recent years after 218 Lewis' operations and 36 Herlock's operations was 9.0%. After analysing experience in combined treatment, the authors failed to reveal any particular advantages over solely surgical treatment, but in view of the lack of other alternatives for improving the results of management of esophageal carcinoma to-date, they believe it expedient to continue study and improve various combinations of preoperative radio-(chemoradio)therapy and operation in large research centres.
作者分析了全苏癌症研究中心采用各种方法治疗食管癌患者37年的经验。展示了1850例患者放疗、手术及综合治疗的近期和远期结果。考虑到手术时肿瘤进程已有相当程度的扩展,作者证实了一期手术并形成胸膜内食管胃吻合术的合理性。近年来,218例Lewis手术和36例Herlock手术的死亡率为9.0%。在分析综合治疗经验后,作者未发现其相对于单纯手术治疗有任何特别优势,但鉴于目前改善食管癌治疗效果缺乏其他选择,他们认为在大型研究中心继续研究并改进术前放疗(放化疗)与手术的各种联合方式是适宜的。