Watanabe Suguru, Minagawa Tadanori, Kagatani Tomoaki, Miura Makoto, Tabayashi Kouichi
Cardiovascular Surgery Tohoku Phamaceutical University Hospital, 1-12-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8512, Japan,
Gen Thorac Cardiovasc Surg. 2014 Nov;62(11):693-5. doi: 10.1007/s11748-013-0271-z. Epub 2013 Jun 7.
Factor XI (FXI) deficiency is rare and associated with bleeding after surgical procedures. We report a case of an 80-year-old woman with severe aortic valve stenosis. FXI deficiency was diagnosed due to prolonged activated partial thromboplastin time. Aortic valve replacement was performed using a porcine bioprosthetic valve. Intra-operation bleeding was controlled by the transfusion of a fresh frozen plasma. The postoperative course was uneventful.
因子 XI(FXI)缺乏症较为罕见,与外科手术后出血有关。我们报告一例80岁患有严重主动脉瓣狭窄的女性病例。因活化部分凝血活酶时间延长而诊断为 FXI 缺乏症。使用猪生物瓣膜进行了主动脉瓣置换术。术中出血通过输注新鲜冰冻血浆得以控制。术后过程顺利。