Departments of Respiratory Medicine (Y-bC, J-aH, CJ, C-hL) and Pathology (L-cG), The First Affiliated Hospital of Soochow University, Suzhou, China.
Am J Med Sci. 2014 Jan;347(1):50-3. doi: 10.1097/MAJ.0b013e318295c821.
There have been no clinical reports on clear cell tumor of the lung (CCTL) based on large studies or epidemiological surveys in the literature. The purpose of this study was to provide a retrospective analysis of CCTL patients in China by reviewing the clinical data of reported CCTL cases.
The China academic journals full-text database search engines were used to collect the related cases from January 1979 to June 2011. The analysis was performed on patients' age, gender, symptom, nodular number, tumor size, lesion localization, chest radiograph or chest computed tomography.
Thirty-nine cases of CCTL were reported in China. The ratio of male:female was 1.29:1. The average age at diagnosis was 43 ± 17 years. Most of them were accidentally discovered on routine chest roentgenogram or computed tomography. The ratio of asymptomatic:symptomatic was 2.25:1 (27:12). Cough, fever, sputum, dyspnea and chest pain occurred frequently in symptomatic patients. Solitary pulmonary nodule on chest radiography was found in 38 patients, and no specific lobar distribution had been noted. The average tumor size was 3.6 ± 2.4 cm in diameter. All patients were diagnosed after thoracotomy, and the postoperative courses were all uneventful.
CCTL is a rare benign tumor with special features of clinical characteristics, radiology and pathology. The diagnosis is based on distinct pathological characteristics. Earlier operation with long-term follow-up is recommended.
在文献中，尚无基于大样本研究或流行病学调查的关于肺透明细胞肿瘤（CCTL）的临床报道。本研究旨在通过回顾已报道的 CCTL 病例的临床资料，对中国的 CCTL 患者进行回顾性分析。
通过中国学术期刊全文数据库检索引擎，收集 1979 年 1 月至 2011 年 6 月的相关病例。对患者的年龄、性别、症状、结节数量、肿瘤大小、病变部位、胸片或胸部 CT 进行分析。
中国共报道 39 例 CCTL。男女比例为 1.29:1。诊断时的平均年龄为 43±17 岁。大多数患者是在常规胸片或 CT 检查中偶然发现的。无症状与有症状患者的比例为 2.25:1（27:12）。有症状患者常出现咳嗽、发热、咳痰、呼吸困难和胸痛等症状。胸部 X 线片显示 38 例患者为孤立性肺结节，无特定的肺叶分布。肿瘤平均直径为 3.6±2.4cm。所有患者均经手术诊断，术后均无并发症。
CCTL 是一种罕见的良性肿瘤，具有独特的临床特征、影像学和病理学特征。诊断基于明显的病理特征。建议尽早手术并长期随访。
