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全膝关节置换术后晚期牛链球菌感染并发感染性心内膜炎并与结肠溃疡相关

Late Streptococcus bovis infection of total knee replacement complicated by infective endocarditis and associated with colonic ulcers.

作者信息

Nagy Mathias Thomas, Hla Sann Minn, Keys Graham Watson

机构信息

Department of Trauma and Orthopaedic Surgery, Macclesfield District General Hospital, Macclesfield, UK.

出版信息

BMJ Case Rep. 2013 Jun 5;2013:bcr2013008709. doi: 10.1136/bcr-2013-008709.

Abstract

Streptococcus bovis is rare cause of late infections after total knee replacement (TKR). This report presents a case of confirmed late septic arthritis following TKR caused by S bovis that was further complicated with infective endocarditis resulting in aortic valve insufficiency in an immunecompetent patient. As an association between S bovis and gastrointestinal malignancies is suggested, a workup for such malignancies was performed that revealed non-malignant ulcers in patient's ascending colon. The patient is currently recovering from his aortic valve replacement surgery and is scheduled to have annual colonoscopies. His knee joint has improved; however, he developed constant pain because of underlying chronic infection in the affected joint and has difficulties mobilising. Therefore, a revision TKR is considered but postponed until he fully recovers from his heart valve surgery.

摘要

牛链球菌是全膝关节置换术(TKR)后晚期感染的罕见病因。本报告介绍了一例确诊的TKR术后由牛链球菌引起的晚期化脓性关节炎病例,该病例在一名免疫功能正常的患者中进一步并发感染性心内膜炎,导致主动脉瓣关闭不全。由于提示牛链球菌与胃肠道恶性肿瘤之间存在关联,因此对该类恶性肿瘤进行了检查,结果显示患者升结肠有非恶性溃疡。患者目前正在从主动脉瓣置换手术中恢复,计划每年进行结肠镜检查。他的膝关节状况有所改善;然而,由于患有关节潜在的慢性感染,他出现了持续疼痛,并且行动困难。因此,考虑进行TKR翻修手术,但推迟到他从心脏瓣膜手术中完全康复之后。

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