Mais Laetitia, Gerome Patrick, Tesse Sylvie, Vincent Edmond
Service d'hépato gastroentérologie, HIA Desgenettes, Lyon, France.
Ann Biol Clin (Paris). 2013 May-Jun;71(3):349-51. doi: 10.1684/abc.2013.0822.
Hepatitis E is rare in France but its increasing frequency makes it an emerging infection. Autochtonous hepatitis E is prevalent, largely confined to older men and currently caused by gentotype 3f. Patients with unexplained hepatitis should be tested by hepatitis E, even in the absence of travel from endemic areas. The diagnosis is based on serological testing (including detection of specific antibodies IgM and IgG, and sometimes by determination of antibody avidity) and nucleic acid amplification techniques which might used first.
戊型肝炎在法国较为罕见,但发病率不断上升使其成为一种新发感染病。散发性戊型肝炎较为普遍,主要集中在老年男性,目前由3f基因型引起。即使没有来自流行地区的旅行史,原因不明的肝炎患者也应进行戊型肝炎检测。诊断基于血清学检测(包括检测特异性抗体IgM和IgG,有时还通过测定抗体亲和力)以及可能首先使用的核酸扩增技术。