Akbay Sinem, Yel Arda, Yıldırımer Ülkü, Can Şule, Dündar Bumin
İzmir Tepecik Training and Research Hospital, Department of Pediatric Endocrinology, İzmir, Turkey.
J Clin Res Pediatr Endocrinol. 2013;5(2):133-5. doi: 10.4274/Jcrpe.905.
Pseudonormoglycemic diabetic ketoacidosis (DKA) is a rare condition and has been reported only in a few adult patients. We present a 15-year-old girl with a 9-year history of type 1 diabetes who presented with euglycemic and extreme hypertriglyceridemia. The acidosis and hypertriglyceridemia resolved with intravenous insulin therapy and rehydration. Hyperlipidemia was the apparent cause of pseudonormoglycemia in this patient. The findings in the present case demonstrate that also in children, DKA can rarely occur without abnormal blood glucose levels. Assessment of the acid-base status, urinary glucose, and ketone readings is therefore important in all diabetic patients who are unwell at admission and have normal glucose levels. In such patients, hyperlipidemia may cause pseudonormoglycemia. An awareness of this rare treatable life-threatening condition is important.
假性正常血糖性糖尿病酮症酸中毒（DKA）是一种罕见病症，仅在少数成年患者中有所报道。我们报告了一名15岁的1型糖尿病女孩，她有9年的糖尿病病史，此次出现血糖正常但甘油三酯极度升高的情况。酸中毒和高甘油三酯血症通过静脉胰岛素治疗和补液得以缓解。高脂血症是该患者假性正常血糖的明显原因。本病例的研究结果表明，即使在儿童中，DKA也很少会在血糖水平正常的情况下发生。因此，对于所有入院时身体不适且血糖水平正常的糖尿病患者，评估酸碱状态、尿糖和酮体读数非常重要。在此类患者中，高脂血症可能导致假性正常血糖。认识到这种罕见但可治疗的危及生命的病症很重要。
