Wakabayashi A, Nakamura Y, Woollley T, Mullin P J, Watanabe H, Ino T, Connolly J E
Arch Surg. 1975 Jul;110(7):802-4. doi: 10.1001/archsurg.1975.01360130034007.
Newly developed all solid state catheter oxygen pressure (PO2) and pH electrodes were evaluated in dogs in respiratory acidosis and hemorrhagic shock. The electrodes were inserted into the blood vessels and thigh muscle by a percutaneous puncture technique. In animals with respiratory acidosis, arterial, venous, and intramuscular pH decreased in parallel as arterial carbon dioxide pressure (PCO2) increased. During severe acidosis, arterial and venous PO2 did not change appreciably, but intramuscular PO2 decreased moderately, indicating decreased tissue perfusion. In animals with hemorrhagic shock, intramuscular PO2 decreased in proportion to the blood loss, whereas the reduction in intramuscular pH and blood pressure lagged behind blood loss. A similar finding was observed during reinfusion of shed blood in surviving animals. In the animals that died, intramuscular PO2 AND PH remained low after the reinfusion of all shed blood, although arterial blood pressure did return to base line levels.
新型全固态导管式氧分压（PO2）和pH电极在患有呼吸性酸中毒和失血性休克的犬类动物身上进行了评估。电极通过经皮穿刺技术插入血管和大腿肌肉。在患有呼吸性酸中毒的动物中，随着动脉二氧化碳分压（PCO2）升高，动脉、静脉和肌肉内的pH值平行下降。在严重酸中毒期间，动脉和静脉PO2没有明显变化，但肌肉内PO2适度下降，表明组织灌注减少。在患有失血性休克的动物中，肌肉内PO2与失血量成比例下降，而肌肉内pH值和血压的降低则滞后于失血量。在存活动物回输 shed 血期间也观察到类似的发现。在死亡的动物中，尽管动脉血压确实恢复到基线水平，但在回输所有 shed 血后，肌肉内PO2和pH值仍然很低。
