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吸食甲麻黄碱继发纵隔气肿。

Pneumomediastinum secondary to mephedrone inhalation.

作者信息

McCullough Chris, Keane Margaret Geraldine, Hillman Toby, Elkhodair Samer

机构信息

Department of Emergency Medicine, University College Hospital, London, UK.

出版信息

BMJ Case Rep. 2013 Jun 7;2013:bcr2013009961. doi: 10.1136/bcr-2013-009961.

DOI:10.1136/bcr-2013-009961
PMID:23749863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3702967/
Abstract

A 23-year-old man presented to the emergency department with severe, central, pleuritic chest pain. The pain was present on waking and exacerbated by movement. On examination, supraclavicular and anterior chest wall surgical emphysema was noted, otherwise examination and initial observations were normal. A chest x-ray and subsequent chest CT demonstrated a pneumomediastium with significant subcutaneous emphysema. There was no history of vomiting or chest trauma, but the patient had inhaled mephedrone, a synthetic stimulant drug, 36 h prior. Pneumomediastinum is an uncommon complication of inhalational drug use.

摘要

一名23岁男性因严重的中央性胸膜炎性胸痛就诊于急诊科。疼痛在醒来时出现,并因活动而加重。检查时,发现锁骨上及前胸壁皮下气肿,其他检查及初始观察均正常。胸部X线及随后的胸部CT显示纵隔气肿伴明显皮下气肿。患者无呕吐或胸部外伤史,但在36小时前吸入了合成兴奋剂药物甲氧麻黄酮。纵隔气肿是吸入性药物使用的一种罕见并发症。

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本文引用的文献

1
Spontaneous subcutaneous emphysema associated with mephedrone usage.与使用甲麻黄碱相关的自发性皮下气肿。
Ann R Coll Surg Engl. 2012 Jan;94(1):e38-40. doi: 10.1308/003588412X13171221499108.
2
Clinical characteristics of mephedrone toxicity reported to the U.K. National Poisons Information Service.向英国国家毒物信息服务中心报告的麦角酸二乙酰胺毒性的临床特征。
Emerg Med J. 2011 Aug;28(8):686-9. doi: 10.1136/emj.2010.096636. Epub 2010 Aug 25.
3
Clinical course and outcome of cocaine-induced pneumomediastinum.可卡因诱导性纵隔气肿的临床病程和转归。
Am J Med Sci. 2010 Jan;339(1):65-7. doi: 10.1097/MAJ.0b013e3181c371da.
4
Spontaneous pneumomediastinum: diagnostic and therapeutic interventions.自发性纵隔气肿:诊断与治疗干预措施
J Cardiothorac Surg. 2008 Nov 3;3:59. doi: 10.1186/1749-8090-3-59.
5
Spontaneous pneumomediastinum: a benign curiosity or a significant problem?自发性纵隔气肿:是良性奇症还是重大问题?
Chest. 2005 Nov;128(5):3298-302. doi: 10.1378/chest.128.5.3298.