Sousa Alexandre de Andrade, Porcaro-Salles José Maria, Soares João Marcos Arantes, de Moraes Gustavo Meyer, Carvalho Jomar Rezende, Silva Guilherme Souza, Savassi-Rocha Paulo Roberto
Faculty of Medicine, Federal Unversity of Minas Gerais, Minas Gerais, Brazil.
Rev Col Bras Cir. 2013 Mar-Apr;40(2):98-103. doi: 10.1590/s0100-69912013000200003.
To evaluate the incidence of pharyngocutaneous fistula after total laryngectomy and try to identify its predictors.
From May 2005 to April 2010, 93 patients underwent total laryngectomy. We evaluated complications during and after surgery and compared them with the following variables: gender, nutritional status, previous tracheotomy, tumor location, type of surgery, TNM staging, prior treatment with chemotherapy and/or radiotherapy, use of flaps for reconstruction and surgical margin. All patients presented with advanced neoplastic disease according to TNM.
14 (15.1%) patients developed postoperative salivary fistula. The mean time to onset of salivary fistula was 3.5 days, with a standard deviation of 13.7 days. Comparing salivary fistula with TNM variables, type of operation and neck dissection, prior tracheotomy, use of flap, preoperative radio and chemotherapy and surgical margin, there was no statistically significant difference (p> 0,05).
The incidence of salivary fistula was 15.1% and no predictive factor for its formation was found.
评估全喉切除术后咽瘘的发生率，并试图确定其预测因素。
2005年5月至2010年4月，93例患者接受了全喉切除术。我们评估了手术期间及术后的并发症，并将其与以下变量进行比较：性别、营养状况、既往气管切开术、肿瘤位置、手术类型、TNM分期、先前的化疗和/或放疗治疗、用于重建的皮瓣使用情况以及手术切缘。根据TNM，所有患者均患有晚期肿瘤疾病。
14例（15.1%）患者发生术后涎瘘。涎瘘发生的平均时间为3.5天，标准差为13.7天。将涎瘘与TNM变量、手术类型和颈部清扫、既往气管切开术、皮瓣使用情况、术前放疗和化疗以及手术切缘进行比较，差异无统计学意义（p>0.05）。
涎瘘的发生率为15.1%，未发现其形成的预测因素。
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