Ochi Nobuaki, Takigawa Nagio, Yasugi Masayuki, Ishida Etsuji, Kawamoto Hirofumi, Taniguchi Akihiko, Harada Daijiro, Hayashi Eiko, Toda Hiroko, Yanai Hiroyuki, Tanimoto Mitsune, Kiura Katsuyuki
Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate school of Medicine, Dentistry and Pharmaceutical sciences, Okayama, Japan.
Int Med Case Rep J. 2010 Feb 25;3:9-12. doi: 10.2147/imcrj.s8093. Print 2010.
Obstructive jaundice sometimes may develop in association with advanced small-cell lung cancer (SCLC); however, SCLC initially presenting with obstructive jaundice is rare. This report presents the cases of two SCLC patients with obstructive jaundice at the initial diagnosis. A 64-year-old male presented with obstructive jaundice due to a tumor at the head of the pancreas. He was diagnosed with SCLC by transbronchial biopsy from a lung tumor in the left upper lobe. Another 74-year-old male was admitted with jaundice due to a tumor in the porta hepatis. He was also diagnosed with SCLC by a fine-needle aspiration biopsy of a lung tumor in the left lower lobe. Both cases were successfully treated with systemic chemotherapy after endoscopic retrograde biliary drainage.
阻塞性黄疸有时可能与晚期小细胞肺癌(SCLC)相关;然而,最初表现为阻塞性黄疸的SCLC很少见。本报告介绍了两名在初诊时伴有阻塞性黄疸的SCLC患者的病例。一名64岁男性因胰头肿瘤出现阻塞性黄疸。通过对左上叶肺肿瘤进行经支气管活检,他被诊断为SCLC。另一名74岁男性因肝门部肿瘤伴黄疸入院。通过对左下叶肺肿瘤进行细针穿刺活检,他也被诊断为SCLC。两例患者在内镜逆行胆管引流术后均成功接受了全身化疗。