髋部骨折手术后输血与限制性输血策略的随机试验。
Randomised trial of blood transfusion versus a restrictive transfusion policy after hip fracture surgery.
作者信息
Parker Martyn J
机构信息
Orthopaedic Research Fellow, Peterborough and Stamford Hospital NHS Foundation Trust, Department of Orthopaedics, Peterborough City Hospital, CBU P.O. Box 211, Core C, Bretton Gate, Peterborough PE3 9GZ, UK.
出版信息
Injury. 2013 Dec;44(12):1916-8. doi: 10.1016/j.injury.2013.04.033. Epub 2013 Jun 4.
BACKGROUND
Debate exists as to what should be the transfusion threshold for patients with anaemia after hip fracture surgery.
METHODS
A total of 200 patients aged 60 years and above with a haemoglobin level of between 8.0 and 9.5gdl(-1) after hip fracture surgery were randomised to receive a transfusion to raise the haemoglobin to at least 10.0gdl(-1) or not to have a transfusion unless definite symptoms of anaemia became apparent. Patients were followed up for 1 year.
RESULTS
There was no statistically significant difference in the outcomes of mortality, hospital stay, regain of mobility or complications between the two groups.
CONCLUSIONS
This study confirms other recent research studies which found that reducing the transfusion threshold to 8.0gdl(-1) appears to be a safe practice for this group of patients.
背景
关于髋部骨折手术后贫血患者的输血阈值应该是多少存在争议。
方法
总共200名60岁及以上的患者，在髋部骨折手术后血红蛋白水平在8.0至9.5g/dl之间，被随机分为两组，一组接受输血以使血红蛋白至少升至10.0g/dl，另一组除非出现明确的贫血症状否则不进行输血。对患者进行了1年的随访。
结果
两组在死亡率、住院时间、活动能力恢复或并发症等结果方面没有统计学上的显著差异。
结论
本研究证实了其他近期的研究，这些研究发现将输血阈值降至8.0g/dl对这组患者似乎是一种安全的做法。
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