Institute of Medical Psychology, University of Gießen, DE-35392 Gießen, Germany.
Acta Derm Venereol. 2014 Jan;94(1):20-5. doi: 10.2340/00015555-1634.
It is known that itch is associated with psychological variables, but it is not known whether personality characteristics, depression or anxiety are predictors of experimentally induced itch in patients with atopic dermatitis (AD). In this study itch was induced in 27 patients with AD and 28 healthy controls by the presentation of an experimental video on crawling insects and skin diseases. Itch intensity was measured by self-ratings and by observing the number of scratch movements. Itch increase was determined by subtracting itch intensity induced by the experimental video from itch intensity induced by a control video. Psychological variables were assessed using validated questionnaires. In patients with AD, depression was a significant predictor of self-rated induced itch (corrected R2 = 0.175); while agreeableness and public self-consciousness were significant predictors of induced scratching (corrected R2 = 0.534). In healthy controls no associations were found. These results imply that a special group of patients with AD might benefit from certain psychological interventions.
已知瘙痒与心理变量有关，但尚不清楚人格特征、抑郁或焦虑是否是特应性皮炎（AD）患者实验性诱发瘙痒的预测因素。在这项研究中，通过呈现关于爬行昆虫和皮肤病的实验视频，在 27 名 AD 患者和 28 名健康对照者中诱发了瘙痒。通过自我评分和观察搔抓次数来测量瘙痒强度。通过从实验视频引起的瘙痒强度中减去对照视频引起的瘙痒强度来确定瘙痒的增加。使用经过验证的问卷评估心理变量。在 AD 患者中，抑郁是自我评估引起的瘙痒的显著预测因素（校正 R2=0.175）；而宜人性和公众自我意识是引起搔抓的显著预测因素（校正 R2=0.534）。在健康对照组中未发现关联。这些结果表明，AD 的一个特殊患者群体可能会从某些心理干预中受益。
