Sherman M E, Mark E J
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston.
Arch Pathol Lab Med. 1990 Aug;114(8):845-51.
We reviewed the cytologic findings in pleural effusions of 36 patients in whom a diffuse epithelioid or biphasic malignant mesothelioma of the pleura developed between 1978 and 1988. Malignant neoplasms were diagnosed in 26 (72%) of the 36 patients. A specific diagnosis of a mesothelioma was rendered or suspected in 64% (23/36 patients). Mesothelioma was favored over adenocarcinoma in 81% (29/36) of patients with positive fluid cytologic findings. The contribution of effusion cytology to the final diagnosis and patient treatment was assessed. These data suggested that a cytologic diagnosis contributed useful information in most patients with malignant epithelioid and biphasic pleural mesotheliomas.
我们回顾了1978年至1988年间36例发生弥漫性上皮样或双相性胸膜恶性间皮瘤患者胸腔积液的细胞学检查结果。36例患者中有26例（72%）被诊断为恶性肿瘤。64%（23/36例患者）做出或怀疑为间皮瘤的明确诊断。在胸腔积液细胞学检查结果为阳性的患者中，81%（29/36）倾向于诊断为间皮瘤而非腺癌。评估了积液细胞学对最终诊断和患者治疗的作用。这些数据表明，细胞学诊断为大多数恶性上皮样和双相性胸膜间皮瘤患者提供了有用信息。
