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多中心研究应用 Y 型支架辅助弹簧圈栓塞治疗颅内动脉瘤

A multicenter study of stent-assisted coiling of cerebral aneurysms with a Y configuration.

机构信息

Department of Neurosurgery, University of Florida, Gainesville, Florida, USA.

出版信息

Neurosurgery. 2013 Sep;73(3):466-72. doi: 10.1227/NEU.0000000000000015.

Abstract

BACKGROUND

Stent-assisted coiling with 2 stents in a Y configuration is a technique for coiling complex wide-neck bifurcation aneurysms.

OBJECTIVE

We sought to provide long-term clinical and angiographic outcomes with Y-stent coiling, which are not currently established.

METHODS

Seven centers provided deidentified, retrospective data on all consecutive patients who underwent stent-assisted coiling for an intracranial aneurysm with a Y-stent configuration.

RESULTS

Forty-five patients underwent treatment by Y-stent coiling. Their mean age was 57.9 years. Most aneurysms were basilar apex (87%), and 89% of aneurysms were unruptured. Mean size was 9.9 mm. Most aneurysms were treated with 1 open-cell and 1 closed-cell stent (51%), with 29% treated with open-open stents and 16% treated with 2 closed-cell stents. Initial aneurysm occlusion was excellent (84% in Raymond grade I or II). Procedural complications occurred in 11% of patients. Mean clinical follow-up was 7.8 months, and 93% of patients had a modified Rankin Scale score of 0 to 2 at last follow-up. Mean angiographic follow-up was 9.8 months, and 92% of patients had Raymond grade I or II occlusion on follow-up imaging. Of those patients with initial Raymond grade III occlusion and follow-up imaging, all but 1 patient progressed to a better occlusion grade (83%; P < .05). Three aneurysms required retreatment because of recanalization (10%). There was no difference in initial or follow-up angiographic occlusion, clinical outcomes, incidence of aneurysm retreatment, or in-stent stenosis among open-open, open-closed, or closed-closed stent groups.

CONCLUSION

In a large multicenter series of Y-stent coiling for bifurcation aneurysms, there were low complication rates and excellent clinical and angiographic outcomes.

摘要

背景

支架辅助的 Y 型双支架技术是一种治疗复杂宽颈分叉部动脉瘤的方法。

目的

我们旨在提供 Y 型支架技术治疗颅内分叉部动脉瘤的长期临床和血管造影结果,这些结果目前尚未确定。

方法

7 个中心提供了使用 Y 型支架进行支架辅助弹簧圈栓塞术的所有连续患者的匿名回顾性数据。

结果

45 名患者接受了 Y 型支架治疗。他们的平均年龄为 57.9 岁。大多数动脉瘤位于基底动脉尖(87%),89%的动脉瘤未破裂。平均大小为 9.9 毫米。大多数动脉瘤采用 1 个开放细胞支架和 1 个封闭细胞支架(51%)治疗,29%的动脉瘤采用开放-开放支架治疗,16%的动脉瘤采用 2 个封闭细胞支架治疗。初始动脉瘤闭塞效果良好(Raymond 分级 I 或 II 级 84%)。11%的患者出现了手术并发症。平均临床随访时间为 7.8 个月,末次随访时 93%的患者改良 Rankin 量表评分为 0-2 分。平均血管造影随访时间为 9.8 个月,92%的患者在随访影像学上显示 Raymond 分级 I 或 II 级闭塞。在初始 Raymond 分级 III 级闭塞且有随访影像学的患者中,除 1 例患者外,所有患者的闭塞程度均有所改善(83%;P<0.05)。有 3 个动脉瘤因再通而需要再次治疗(10%)。在开放-开放、开放-封闭和封闭-封闭支架组之间,初始或随访的血管造影闭塞、临床结局、动脉瘤再治疗的发生率和支架内狭窄无差异。

结论

在一个大型多中心 Y 型支架治疗分叉部动脉瘤的系列研究中,并发症发生率低,临床和血管造影结果良好。

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