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[一岁以下过敏性儿童的研究。针对蛋清、牛奶和大豆的IgE及IgG4抗体滴度的测定]

[The study of allergic children under one-year old. The measurement of IgE and IgG4 antibody titers to egg white, milk and soybean].

作者信息

Koya N

机构信息

Department of Second Pediatrics, Toho University.

出版信息

Arerugi. 1990 Mar;39(3):330-8.

PMID:2375685
Abstract

We measured the IgE and IgG4 antibody titers to egg white, and soybean of 94 allergic children under one year. (21 wheezy children, 35 atopic dermatitis, 34 wheezy children with atopic dermatitis, and 4 other allergic children). The results were as follows; 1) The positive ratio of IgE antibody titers to egg white was higher than the other IgE antibody titers, and of IgG4 antibody titers to milk was higher than the other IgG4 antibody titers. 2) Of each allergic symptoms, the positive ratio of IgG4 antibody titers to milk was higher than the others in wheezy children group. And the positive ratio of IgE antibody titers to egg white and milk were higher than the others in atopic children and wheezy children with atopic dermatitis. 3) The positive ratio of IgE antibody titers to egg white and milk were higher than the others in the group showed IgE RIST more than 21 IU/ml, and then the positive ratio of IgE antibody titers to egg white, milk and soybean and IgG4 antibody titers to egg white were higher than the others in the group showed eosinophil counts more than 301/mm3.

摘要

我们检测了94名1岁以下过敏儿童针对蛋清和大豆的IgE及IgG4抗体滴度。(21名喘息儿童、35名特应性皮炎儿童、34名喘息合并特应性皮炎儿童以及4名其他过敏儿童)。结果如下:1)针对蛋清的IgE抗体滴度阳性率高于其他IgE抗体滴度,针对牛奶的IgG4抗体滴度阳性率高于其他IgG4抗体滴度。2)在各过敏症状中,喘息儿童组针对牛奶的IgG4抗体滴度阳性率高于其他症状。在特应性儿童及喘息合并特应性皮炎儿童中,针对蛋清和牛奶的IgE抗体滴度阳性率高于其他症状。3)在IgE RIST大于21 IU/ml的组中,针对蛋清和牛奶的IgE抗体滴度阳性率高于其他组,而在嗜酸性粒细胞计数大于301/mm3的组中,针对蛋清、牛奶和大豆的IgE抗体滴度以及针对蛋清的IgG4抗体滴度阳性率高于其他组。

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