Mohan Prasoon P, Hamblin Michael H
Diagnostic and Interventional Radiology, St. Francis Hospital, 355 Ridge Avenue, Evanston, IL, 60202, USA,
Cardiovasc Intervent Radiol. 2014 Apr;37(2):337-42. doi: 10.1007/s00270-013-0665-4. Epub 2013 Jun 12.
The purpose of this study is national-level comparison of the endovascular (EVAR) and open repair (OAR) of ruptured abdominal aortic aneurysm (AAA) in the United States from 2001 to 2010.
The data were obtained from nationwide inpatient sample from the Department of Health and Human Services. Ruptured AAA treated by OAR or EVAR were selected using combination ICD-9 codes.
There were 42,126 cases of ruptured AAA of which 8,140 (19.3%) were repaired by EVAR. EVAR patients were older (74.1 vs. 72.8 years, p < 0.001) and had higher incidence of comorbidities compared with OAR group. EVAR patients had lower in-hospital mortality (25.9 vs. 39.1%, p < 0.001) and shorter hospital stay (10.4 vs. 13.7 days, p < 0.001). More patients were discharged home following EVAR (36.8 vs. 21.5%, p < 0.001). There was reduced need for institutional rehabilitation following EVAR (26.3 vs. 29.1%, p < 0.001). Females had significantly higher mortality compared with males after both EVAR (32.2 vs. 24.1%, p < 0.001) and OAR (46.2 vs. 36.9%, p < 0.001). The hospital mortality (41.3-25.8%, p < 0.001) and mean length of stay (11.8-9.7 days, p < 0.01) of EVAR steadily improved over the study period.
National level comparison of data from the past decade shows that in suitable cases, EVAR for ruptured AAA is associated with reduced hospital mortality, shorter hospital stay, and reduced need for rehabilitation. EVAR outcomes showed consistent improvement with time. Regardless of the type of repair, women had higher mortality compared with men.
本研究旨在对2001年至2010年美国破裂腹主动脉瘤(AAA)的血管内修复术(EVAR)和开放修复术(OAR)进行国家级比较。
数据取自美国卫生与公众服务部的全国住院患者样本。使用ICD - 9编码组合筛选出接受OAR或EVAR治疗的破裂AAA患者。
共有42126例破裂AAA病例,其中8140例(19.3%)接受了EVAR修复。与OAR组相比,接受EVAR治疗的患者年龄更大(74.1岁对72.8岁,p < 0.001),合并症发生率更高。接受EVAR治疗的患者住院死亡率更低(25.9%对39.1%,p < 0.001),住院时间更短(10.4天对13.7天,p < 0.001)。接受EVAR治疗后更多患者出院回家(36.8%对21.5%,p < 0.001)。接受EVAR治疗后机构康复需求减少(26.3%对29.1%,p < 0.001)。女性在接受EVAR(32.2%对24.1%,p < 0.001)和OAR(46.2%对36.9%,p < 0.001)治疗后的死亡率均显著高于男性。在研究期间,EVAR的医院死亡率(41.3% - 25.8%,p < 0.001)和平均住院时间(11.8天 - 9.7天,p < 0.01)稳步改善。
过去十年的国家级数据比较表明,在合适的病例中,破裂AAA的EVAR与降低医院死亡率、缩短住院时间以及减少康复需求相关。EVAR的治疗效果随时间持续改善。无论采用何种修复方式,女性的死亡率均高于男性。