Martín de Pumarejo M, Lugo C E, Alvarez-Ruiz J R, Colón-Santini J L
Departamento de Pediatría, Escuela de Medicina, Universidad de Puerto Rico, San Juan.
Bol Asoc Med P R. 1990 May;82(5):227-33.
Oral rehydration solutions containing 50-90 mEq/L of sodium (Na+) have recently been recommended for the ambulatory management of children with acute diarrhea in the United States. We conducted a randomized study comparing the use of a commercial oral rehydration solution (Rehydralyte), containing 75 mEq/L of Na with the usual method of rehydration with an intravenous solution. Patients treated in the University Pediatric Hospital Emergency Room with acute diarrhea were randomly chosen to receive the oral rehydration solution (Rehydralyte) (Group A), control patients (Group B) were hydrated with the usual intravenous fluids, ie, Ringer's Lactate and then a solution of 56 mEq/L of Na. All patients received orientation about this modality of treatment. Both groups were compared as for weight gain, metabolic parameters, duration of diarrhea, impact on complications associated with use of intravenous solution and cost impact. When both groups were compared there were no differences in measurements of clinical, laboratory data and outcome. Advantages of oral rehydration on cost containment and less human suffering were demonstrated. It can be concluded that in Puerto Rican children oral rehydration solution containing 75 mEq/L Na may be used safely for the treatment of acute diarrhea on ambulatory basis.
最近,美国推荐使用含50 - 90毫当量/升钠(Na +)的口服补液溶液来门诊治疗急性腹泻患儿。我们进行了一项随机研究,比较使用含75毫当量/升钠的市售口服补液溶液(口服补液盐)与常用的静脉补液方法。在大学儿科医院急诊室治疗急性腹泻的患者被随机选择接受口服补液溶液(口服补液盐)(A组),对照组患者(B组)用常用的静脉输液即乳酸林格氏液,然后用含56毫当量/升钠的溶液进行补液。所有患者均接受了关于这种治疗方式的指导。比较两组患者的体重增加、代谢参数、腹泻持续时间、对静脉输液相关并发症的影响以及成本影响。比较两组时,临床、实验室数据和结果测量方面没有差异。证明了口服补液在控制成本和减少患者痛苦方面的优势。可以得出结论,在波多黎各儿童中,含75毫当量/升钠的口服补液溶液可安全用于门诊治疗急性腹泻。