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在院外人群中使用基线和间歇性心电图记录进行心房颤动筛查。

Screening for atrial fibrillation with baseline and intermittent ECG recording in an out-of-hospital population.

出版信息

BMC Cardiovasc Disord. 2013 Jun 10;13:41. doi: 10.1186/1471-2261-13-41.

DOI:10.1186/1471-2261-13-41
PMID:23758799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3682914/
Abstract

BACKGROUND

the objective of this study is to investigate the detection rate of undiagnosed atrial fibrillation (AF) with short intermittent ECG recordings during four weeks among out-of-hospital patients, having at least one additional risk factor (CHADS2) for stroke.

DESIGN

Cross-sectional study.

SETTING

Eight family practice centres and two hospital-based out-patient clinics in Sweden.

SUBJECTS

989 out-of-hospital patients, without known AF, having one or more risk factors associated with stroke (CHADS2).

INTERVENTIONS

All individuals were asked to perform 10-second handheld ECG recordings during 28 days, twice daily and when having palpitations.

MAIN OUTCOME MEASURES

Episodes of AF on handheld ECG recordings were defined as irregular supraventricular extrasystoles in series with a duration of 10 seconds.

RESULTS

928 patients completed registration. AF was found in 35 of 928 patients; 3.8% (95% confidence interval [CI] 2.7-5.2). These 35 patients had a mean age of 70.7 years (SD ± 7.7; range 53-85) and a median CHADS2 of 2 (range 1-4).

CONCLUSIONS

Intermittent handheld ECG recording over a four week period had a detection rate of 3.8% newly diagnosed AF, in a population of 928 out-of-hospital patients having at least one additional risk factor for stroke. Intermittent handheld ECG registration is a feasible method to detect AF in patients with an increased risk of stroke in whom oral anticoagulation (OAC) treatment is indicated.

摘要

背景

本研究旨在调查在 28 天内,通过四周的间歇性短程心电图记录,检测出患有至少一种中风额外危险因素(CHADS2)的院外患者中未确诊心房颤动(AF)的检出率。

设计

横断面研究。

地点

瑞典的 8 个家庭医疗中心和 2 个医院门诊。

对象

989 名院外患者,无已知的 AF,具有一个或多个与中风相关的危险因素(CHADS2)。

干预措施

所有患者均被要求在 28 天内每天进行两次 10 秒手持心电图记录,出现心悸时随时记录。

主要观察指标

手持心电图记录中的 AF 发作定义为不规则的室上性早搏连续发生,持续时间为 10 秒。

结果

928 名患者完成了登记。在 928 名患者中发现 35 例 AF,检出率为 3.8%(95%置信区间 [CI] 2.7-5.2)。这些 35 名患者的平均年龄为 70.7 岁(SD ± 7.7;范围 53-85),CHADS2 中位数为 2(范围 1-4)。

结论

在 928 名至少有一个中风额外危险因素的院外患者中,通过四周间歇性手持心电图记录,新诊断 AF 的检出率为 3.8%。间歇性手持心电图记录是一种可行的方法,可用于检测具有中风风险增加且需要口服抗凝治疗(OAC)的患者中的 AF。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/9d411269112b/1471-2261-13-41-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/7e20c444ffc7/1471-2261-13-41-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/67e1191620a5/1471-2261-13-41-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/7c7c015de504/1471-2261-13-41-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/9d411269112b/1471-2261-13-41-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/7e20c444ffc7/1471-2261-13-41-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/67e1191620a5/1471-2261-13-41-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/7c7c015de504/1471-2261-13-41-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e74/3682914/9d411269112b/1471-2261-13-41-4.jpg

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