Wang Hao, Chen Ping
Department of Gastrointestinal Surgery, Su Bei People's Hospital of Jiangsu Province, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
Oncol Lett. 2013 May;5(5):1497-1500. doi: 10.3892/ol.2013.1218. Epub 2013 Feb 28.
Unexpected clinical and/or imaging evidence of the recurrence of gastrointestinal stromal tumors soon after surgical resection may be complicated due to certain biological behavioral features of gastrointestinal stromal tumors. However, local hemostatic materials routinely used in abdominal surgery to achieve hemostasis intraoperatively may cause a foreign-body reaction, which appears to be indistinguishable from recurrent tumors in imaging studies. Thus, a second examination may be necessary to settle the true nature of the findings in such cases. If the resection and examination reveals a recurrent tumor, further proper oncological treatment is warranted, whereas if a foreign-body reaction is observed, radical or potentially harmful therapy may be withheld or cancelled. The present study retrospectively analyzes the case of an 83-year-old male patient who presented with a recurrent gastrointestinal stromal tumor four months after surgical resection, which was later identified as an intra-abdominal foreign-body granuloma caused by retained Surgicel residue. The present study aimed to demonstrate why foreign-body granuloma induced by local hemostatic materials should be incorporated into the differential diagnosis of recurrent gastrointestinal stromal tumors post-operatively, particularly soon after surgical resection has been performed.
胃肠道间质瘤手术切除后不久出现意外的临床和/或影像学复发证据，可能因其某些生物学行为特征而变得复杂。然而，腹部手术中常规用于术中止血的局部止血材料可能会引起异物反应，在影像学研究中，这种反应似乎与复发性肿瘤难以区分。因此，在这种情况下可能需要进行二次检查以确定检查结果的真实性质。如果切除和检查显示为复发性肿瘤，则有必要进行进一步适当的肿瘤治疗，而如果观察到异物反应，则可能会暂停或取消根治性或潜在有害的治疗。本研究回顾性分析了一名83岁男性患者的病例，该患者在手术切除四个月后出现复发性胃肠道间质瘤，后来被确定为由保留的速即纱残留物引起的腹腔内异物肉芽肿。本研究旨在证明为什么由局部止血材料引起的异物肉芽肿应纳入术后复发性胃肠道间质瘤的鉴别诊断中，尤其是在手术切除后不久。
