Niaussat P M, Drouet J, Bagnis R, Deloince R, Chanfour B
C R Seances Soc Biol Fil. 1975;169(4):912-9.
Two fractions of ciguatoxic extracts were isolated by chromatography. The first showed anticholinesterasic properties, while the other acted directly on the muscular fibre. These findings were histoenzymologically confirmed. Controls with non-toxic extracts of fishes from the coral benthos reinforce the theory of the ecological origins of ciguatoxins.
通过色谱法分离出了两份雪卡毒素提取物。第一份显示出抗胆碱酯酶特性,而另一份则直接作用于肌纤维。这些发现得到了组织酶学的证实。用来自珊瑚底栖生物的无毒鱼类提取物进行的对照实验强化了雪卡毒素的生态起源理论。