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Peritraumatic heart rate and posttraumatic stress disorder in patients with severe burns.严重烧伤患者创伤时心率与创伤后应激障碍。
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Heart rate measured in the acute aftermath of trauma can predict post-traumatic stress disorder: a prospective study in motor vehicle accident survivors.创伤后即刻测量的心率可预测创伤后应激障碍:机动车事故幸存者的前瞻性研究。
Eur Psychiatry. 2011 Nov;26(8):508-12. doi: 10.1016/j.eurpsy.2010.06.006. Epub 2010 Sep 1.
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Lightning injury: a review.雷击伤:综述
Burns. 2008 Aug;34(5):585-94. doi: 10.1016/j.burns.2007.11.006. Epub 2008 Apr 18.
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Stress hormones and post-traumatic stress disorder in civilian trauma victims: a longitudinal study. Part II: the adrenergic response.应激激素与平民创伤受害者的创伤后应激障碍:一项纵向研究。第二部分:肾上腺素能反应。
Int J Neuropsychopharmacol. 2008 May;11(3):373-80. doi: 10.1017/S1461145707008139. Epub 2007 Oct 31.
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Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study.哌唑嗪对平民创伤后应激障碍患者客观睡眠指标及临床症状的影响:一项安慰剂对照研究。
Biol Psychiatry. 2008 Mar 15;63(6):629-32. doi: 10.1016/j.biopsych.2007.07.001. Epub 2007 Sep 14.
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New onset postural tachycardia syndrome following lightning injury.雷击伤后新发姿势性心动过速综合征
Pacing Clin Electrophysiol. 2007 Aug;30(8):1036-8. doi: 10.1111/j.1540-8159.2007.00807.x.
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Effect of age on adrenergic and vagal baroreflex sensitivity in normal subjects.年龄对正常受试者肾上腺素能和迷走神经压力反射敏感性的影响。
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Pharmacologic reduction of CNS noradrenergic activity in PTSD: the case for clonidine and prazosin.创伤后应激障碍中中枢神经系统去甲肾上腺素能活性的药物性降低:可乐定和哌唑嗪的情况
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A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder.一项关于哌唑嗪治疗创伤后应激障碍退伍军人创伤性噩梦和睡眠障碍的平行组安慰剂对照研究。
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雷击后中枢性高肾上腺素能状态。

Central hyperadrenergic state after lightning strike.

机构信息

Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

出版信息

Clin Auton Res. 2013 Aug;23(4):169-73. doi: 10.1007/s10286-013-0197-7. Epub 2013 Jun 13.

DOI:10.1007/s10286-013-0197-7
PMID:23761114
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3737249/
Abstract

OBJECTIVE

To describe and review autonomic complications of lightning strike.

METHODS

Case report and laboratory data including autonomic function tests in a subject who was struck by lightning.

RESULTS

A 24-year-old man was struck by lightning. Following that, he developed dysautonomia, with persistent inappropriate sinus tachycardia and autonomic storms, as well as posttraumatic stress disorder (PTSD) and functional neurologic problems.

INTERPRETATION

The combination of persistent sinus tachycardia and episodic exacerbations associated with hypertension, diaphoresis, and agitation was highly suggestive of a central hyperadrenergic state with superimposed autonomic storms. Whether the additional PTSD and functional neurologic deficits were due to a direct effect of the lightning strike on the central nervous system or a secondary response is open to speculation.

摘要

目的

描述并回顾雷击导致的自主神经并发症。

方法

对 1 名被雷击的患者进行病例报告和包括自主功能测试在内的实验室数据回顾。

结果

一名 24 岁男性被雷击。之后,他出现了自主神经紊乱,表现为持续性不适当窦性心动过速和自主神经风暴,以及创伤后应激障碍(PTSD)和功能性神经问题。

解释

持续性窦性心动过速与高血压、出汗和激越相关的阵发性加重相结合,强烈提示存在中枢性高肾上腺素能状态,伴有自主神经风暴。额外的 PTSD 和功能性神经缺损是否是由于闪电直接作用于中枢神经系统或继发反应引起的,这仍存在争议。