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在美国提供急诊护理的医院中,氰化物解毒剂储备不足。

Insufficient stocking of cyanide antidotes in US hospitals that provide emergency care.

作者信息

Gasco Lucas, Rosbolt Margaret B, Bebarta Vikhyat S

机构信息

Department of Pharmacy, David Grant Medical Center, CA, USA.

出版信息

J Pharmacol Pharmacother. 2013 Apr;4(2):95-102. doi: 10.4103/0976-500X.110875.

Abstract

OBJECTIVE

To identify the influence of catchment area, trauma center designation, hospital size, subspecialist employment, funding source, and other hospital characteristics on cyanide antidote stocking choice in US hospitals that provides emergency care.

MATERIALS AND METHODS

A web-based survey was sent out to pharmacy managers through two listservs; the American Society of Health-Systems Pharmacists and the American College of Clinical Pharmacy. A medical marketing company also broadcasted the survey to 2,659 individuals. We collected data on hospital characteristics (size, state, serving population, etc.,) to determine what influenced the hospital's stocking choice.

RESULTS

The survey response rate was approximately 10% (n = 286). Thirty-eight hospitals (16%) stocked at least 4 antidote kits. Safety profile, recommendations from a poison control center, and ease of use had the strongest influence on stocking decisions.

CONCLUSIONS

Survey of 286 US hospital pharmacy managers, 38/234 (16%) hospitals had sufficient stocking of cyanide antidotes. Antidote preference was based on safety, ease of use, and recommendations by the local poison center, over cost.

摘要

目的

确定集水区、创伤中心指定、医院规模、专科医生聘用情况、资金来源以及其他医院特征对美国提供急诊护理的医院中氰化物解毒剂储备选择的影响。

材料与方法

通过两个邮件列表向药房经理发送基于网络的调查问卷;美国卫生系统药师协会和美国临床药学学院。一家医疗营销公司也向2659人传播了该调查问卷。我们收集了医院特征(规模、所在州、服务人群等)的数据,以确定是什么影响了医院的储备选择。

结果

调查回复率约为10%(n = 286)。38家医院(16%)储备了至少4套解毒剂试剂盒。安全性、来自中毒控制中心的建议以及易用性对储备决策的影响最大。

结论

对286名美国医院药房经理进行的调查显示,234家医院中有38家(16%)有足够的氰化物解毒剂储备。解毒剂的选择基于安全性、易用性以及当地中毒控制中心的建议,而非成本。

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本文引用的文献

1
Sodium thiosulfate: new hope for the treatment of calciphylaxis.
Semin Dial. 2010 May-Jun;23(3):258-62. doi: 10.1111/j.1525-139X.2010.00738.x.
4
Expert consensus guidelines for stocking of antidotes in hospitals that provide emergency care.
Ann Emerg Med. 2009 Sep;54(3):386-394.e1. doi: 10.1016/j.annemergmed.2009.01.023. Epub 2009 May 5.
5
Role of hydroxocobalamin in acute cyanide poisoning.
Ann Pharmacother. 2008 May;42(5):661-9. doi: 10.1345/aph.1K559. Epub 2008 Apr 8.
6
Enhancing public health preparedness for a terrorist attack involving cyanide.
J Emerg Med. 2008 Jul;35(1):59-65. doi: 10.1016/j.jemermed.2007.03.040. Epub 2007 Aug 29.
7
Sodium thiosulfate or hydroxocobalamin for the empiric treatment of cyanide poisoning?
Ann Emerg Med. 2007 Jun;49(6):806-13. doi: 10.1016/j.annemergmed.2006.09.021. Epub 2006 Nov 13.
8
New developments in antidotes.
Med Clin North Am. 2005 Nov;89(6):1379-97. doi: 10.1016/j.mcna.2005.06.001.
9
Nitrite and thiosulfate therapy in cyanide poisoning.
J Am Med Assoc. 1952 May 10;149(2):113-9. doi: 10.1001/jama.1952.02930190015004.
10
Availability of antidotes in Quebec hospitals before and after dissemination of guidelines.
Am J Health Syst Pharm. 2003 Nov 15;60(22):2345-9. doi: 10.1093/ajhp/60.22.2345.

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