Chamsi-Pasha Mohammed A R, Alraies M Chadi, Alraiyes Abdul Hamid, Hsi Eric D
Department of Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Case Rep Hematol. 2013;2013:291518. doi: 10.1155/2013/291518. Epub 2013 May 16.
Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome, characterized clinically by fever, splenomegaly, cytopenia, and high ferritin. Infectious causes have been associated with secondary HLH, with viruses being the most common. We report a case of Mycobacterium avium complex-associated HLH in a sickle cell anemia patient. To the best of our knowledge, this association has never been reported in sickle cell anemia.
噬血细胞性淋巴组织细胞增生症(HLH)是一种罕见的高炎症综合征,临床特征为发热、脾肿大、血细胞减少和铁蛋白升高。感染性病因与继发性HLH有关,其中病毒最为常见。我们报告了一例镰状细胞贫血患者发生鸟分枝杆菌复合体相关HLH的病例。据我们所知,这种关联在镰状细胞贫血中从未有过报道。