Abu-Zaid Ahmed, Azzam Ayman, Al-Wusaibie Ahmed, Bin Makhashen Maraei, Jarman Abdulaziz, Amin Tarek
College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Case Rep Oncol Med. 2013;2013:431743. doi: 10.1155/2013/431743. Epub 2013 May 21.
Merkel cell carcinoma (MCC) is an uncommon highly aggressive skin malignancy with an increased tendency to recur locally, invade regional lymph nodes, and metastasize distally to lung, liver, brain, bone, and skin. The sun-exposed skin of head and neck is the most frequent site of involvement (55%). We report the case of a 63-year-old Caucasian male patient who presented with a recurrent left inguinal mass for the third time after surgical resection with safe margins and no postoperative radio- or chemotherapy. The presented mass was excised, and pathological diagnosis revealed recurrent MCC. The patient underwent postoperative radiation therapy, and 6 months later, he developed a right groin mass which was resected and pathological diagnosis confirmed metastatic MCC. Six months later, patient developed an oropharyngeal mass which was unresectable, and pathological biopsy confirmed metastatic MCC. Patient was offered palliative radio- and chemotherapy. In this paper, we also present a brief literature review on MCC.
默克尔细胞癌（MCC）是一种罕见的侵袭性很强的皮肤恶性肿瘤，具有局部复发、侵犯区域淋巴结以及远处转移至肺、肝、脑、骨和皮肤的倾向增加。头颈部暴露于阳光下的皮肤是最常受累的部位（55%）。我们报告了一例63岁的白种男性患者，该患者在接受了安全切缘的手术切除且未进行术后放疗或化疗后，第三次出现左侧腹股沟复发性肿块。切除了所出现的肿块，病理诊断为复发性MCC。患者接受了术后放射治疗，6个月后，他出现了右侧腹股沟肿块，该肿块被切除，病理诊断证实为转移性MCC。6个月后，患者出现了一个无法切除的口咽肿块，病理活检证实为转移性MCC。患者接受了姑息性放疗和化疗。在本文中，我们还对MCC进行了简要的文献综述。
