Tseng Hui-Wen, Tseng Hui-Hwa, Wu Chieh-Shan
Kaohsiung Veterans General Hospital, Taiwan.
Cutis. 2013 Apr;91(4):194-7.
Confluent and reticulate papillomatosis (CRP) (also known as Gougerot-Carteaud syndrome) is a rare disorder that usually presents sporadically, with onset typically occurring in young .adulthood. We present 2 cases of CRP with typical clinical manifestations of scaly, dull, brownish, confluent and reticulate macules and patches. On examination using a potassium hydroxide (KOH) preparation and Periodic acid-Schiff (PAS) stain, both patients' lesions were negative for fungal elements; in patient 2, bacteria colonies accumulated in follicular orifices without perifollicular inflammation in the dermis. Both patients responded well to treatment with oral minocycline and topical tazarotene and showed clearance of CRP lesions at 12- and 8-month follow-up, respectively.
融合性网状乳头瘤病（CRP）（也称为古热罗 - 卡托综合征）是一种罕见的疾病，通常呈散发性出现，发病通常发生在青年期。我们报告2例CRP患者，其具有典型的临床表现，即鳞屑性、暗淡、褐色、融合性和网状的斑疹和斑块。使用氢氧化钾（KOH）制剂和过碘酸希夫（PAS）染色检查时，两名患者的皮损真菌成分均为阴性；在患者2中，细菌菌落积聚在毛囊口，真皮中无毛囊周围炎症。两名患者口服米诺环素和外用他扎罗汀治疗反应良好，分别在12个月和8个月的随访中CRP皮损消退。
