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[使用维生素A和E纠正振动影响下的免疫反应]

[Use of vitamins A and E for correction of the immune response to effects of vibration].

作者信息

Prokopenko L G, Iakovleva E A

出版信息

Gig Tr Prof Zabol. 1990(4):32-5.

PMID:2376341
Abstract

A sharp decline in the development of humoral immune response to sheep's erythrocytes was identified in rats after vibrational effect. Retinol acetate (RA) and tocopherol acetate (TA) injections markedly increased its development. In rats affected with vibration, after RA injections the spleen adhesive cells incubate (SACI) suppresses humoral immune response development, and the spleen non-adhesive cell incubate (SNCI) stimulates it considerably. In TA-injected rats, both SACI and SNCI do not influence the development of humoral immune response. The splenocytes of intact rats, treated with TA-injected rats' muscle incubate, do not exert immunosuppressive factors, as contrary to the splenocytes treated with RA-injected rats' muscle incubate.

摘要

在振动作用后,大鼠对绵羊红细胞的体液免疫反应发展出现急剧下降。注射醋酸视黄醇(RA)和醋酸生育酚(TA)可显著促进其发展。在受振动影响的大鼠中,注射RA后,脾黏附细胞培养液(SACI)抑制体液免疫反应发展,而脾非黏附细胞培养液(SNCI)则显著刺激其发展。在注射TA的大鼠中,SACI和SNCI均不影响体液免疫反应的发展。与用注射RA的大鼠肌肉培养液处理的脾细胞相反,用注射TA的大鼠肌肉培养液处理的完整大鼠的脾细胞不产生免疫抑制因子。

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