Unit of PharmacoEpidemiology & PharmacoEconomics (PE2), Department of Pharmacy, University of Groningen, Groningen, The Netherlands.
Expert Rev Pharmacoecon Outcomes Res. 2013 Jun;13(3):285-92. doi: 10.1586/erp.13.20.
Research databases with large numbers of prescriptions in observational settings can provide valuable information in addition to the initial randomized controlled trials. This paper reports on the development of prescription database IADB, formerly known as InterAction Database. IADB contains prescriptions from 54 community pharmacies in The Netherlands and covers a population of 500,000 people. Both the age distribution and the prevalence of drugs used are comparable to a large extent with the Dutch population. The representativeness of the population covered is examined by comparing population composition and drug use with data of the whole Dutch population. Enriching IADB with, among others, clinical parameters by linking to other databases is explored. A strong and unique aspect of IADB is the possibility to track patients over time, even when they receive their medication from different pharmacies. The authors conclude IADB is a useful tool for pharmacoepidemiological and pharmacoeconomic outcomes research.
研究数据库中包含大量的处方信息，这些信息除了最初的随机对照试验外，还能提供有价值的信息。本文介绍了处方数据库 IADB 的开发情况，该数据库以前称为 InterAction Database。IADB 包含来自荷兰 54 家社区药店的处方信息，覆盖了 50 万人的人群。年龄分布和药物使用的流行程度在很大程度上与荷兰人口相似。通过将人群组成和药物使用与荷兰总人口数据进行比较，考察了所涵盖人群的代表性。探讨了通过与其他数据库链接等方式为 IADB 丰富临床参数等内容的可能性。IADB 的一个强大而独特的方面是能够跟踪患者随时间的变化情况，即使他们从不同的药店获得药物。作者得出结论，IADB 是进行药物流行病学和药物经济学结果研究的有用工具。
