Bischoff C, Klingelhöfer J, Conrad B
Neurologische Kinik der Technischen Universität München.
Fortschr Neurol Psychiatr. 1990 Jun;58(6):237-40. doi: 10.1055/s-2007-1001187.
10 patients suffering from a widespread continuous fasciculation of the lower extremities without any other neurological signs and symptoms are presented. A follow up study of 6 of these patients could be done. The fasciculation potentials were polyphasic with changing shape from discharge to discharge and appeared irregularly in most of the muscles of the legs. In 5 patients no change of clinical and neurophysiological signs could be detected over the period of observation, whereas in one patient a sensory polyneuropathy was evident in course of time. The findings illustrate that a state of widespread continuous fasciculations without other signs and symptoms is not predicative for the development of a amyotrophic lateral sclerosis.
本文报告了10例下肢广泛持续性肌束震颤但无其他神经体征和症状的患者。对其中6例患者进行了随访研究。肌束震颤电位多相，每次放电时形状改变，且在腿部大多数肌肉中不规则出现。在5例患者中，观察期间未发现临床和神经生理学体征有变化，而在1例患者中，随着时间推移出现了感觉性多发性神经病。这些发现表明，广泛持续性肌束震颤且无其他体征和症状的状态并不能预测肌萎缩侧索硬化的发生。
