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美国男性因下尿路症状到急诊科就诊的发生率和治疗模式。

Incidence and treatment patterns in males presenting with lower urinary tract symptoms to the emergency department in the United States.

机构信息

Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada; Department of Urology, Ruhr University Bochum, Marienhospital, Herne, Germany.

出版信息

J Urol. 2013 Nov;190(5):1798-804. doi: 10.1016/j.juro.2013.05.112. Epub 2013 Jun 11.

Abstract

PURPOSE

Due to varying clinical definitions of lower urinary tract symptoms, it has been difficult to determine comparable prevalence and incidence rates of lower urinary tract symptoms and their treatment modalities. We assessed the incidence of emergency department visits in men with lower urinary tract symptoms who presented to emergency departments in the United States and factors associated with an increased likelihood of hospitalization.

MATERIALS AND METHODS

Emergency department visits from 2006 to 2009 associated with a primary diagnosis of lower urinary tract symptoms using established criteria were abstracted from the Nationwide Emergency Department Sample. Age adjusted incidence rates of emergency department visits and charges were calculated. We performed multivariable analysis to examine patient and hospital characteristics of those hospitalized and those with benign prostatic hyperplasia related adverse events.

RESULTS

A weighted estimate of 1,178,423 emergency department visits for lower urinary tract symptoms was recorded with a national incidence of 197.6/100,000 males per year. A total of 112,288 visits (9.5%) resulted in hospitalization. Adverse events were identified in 734,269 patients (62.3%). The most common adverse events were catheterization in 44.6% of cases, infection in 17.4%, hematuria in 9.6%, bladder stones in 1.7%, hydronephrosis in 1.2% and acute renal failure in 0.1%. On multivariable analysis independent predictors of hospital admission included comorbidities, socioeconomic status, hospital characteristics and adverse events such as sepsis, acute renal failure and hydronephrosis. Independent predictors of adverse events included patient age, year of visit, socioeconomic status, hospital characteristics and concomitant neurological disease. In 2009 total emergency department charges for lower urinary tract symptoms were $494,981,922.

CONCLUSIONS

The number of men with lower urinary tract symptoms who visit the emergency department has remained stable, while emergency department charges have increased by 40%. The rate of adverse events increased during the study period. These findings might suggest over reliance on medical and conservative therapy in the contemporary era.

摘要

目的

由于下尿路症状的临床定义各不相同,因此很难确定可比的下尿路症状的患病率和发病率以及其治疗方式。我们评估了美国急诊部就诊的下尿路症状男性的急诊就诊发生率以及与住院可能性增加相关的因素。

材料与方法

使用既定标准,从全国急诊部样本中提取 2006 年至 2009 年与下尿路症状的主要诊断相关的急诊就诊记录。计算了急诊就诊的年龄调整发生率和费用。我们进行了多变量分析,以检查住院患者和与良性前列腺增生相关不良事件患者的患者和医院特征。

结果

记录了 1178423 例下尿路症状的加权估计急诊就诊,全国每年每 100000 名男性的发病率为 197.6/100000。共有 112288 例就诊(9.5%)导致住院。在 734269 例患者(62.3%)中发现了不良事件。最常见的不良事件是 44.6%的病例中进行导尿,17.4%的感染,9.6%的血尿,1.7%的膀胱结石,1.2%的肾积水和 0.1%的急性肾衰竭。多变量分析表明,住院的独立预测因素包括合并症、社会经济状况、医院特征以及不良事件,如败血症、急性肾衰竭和肾积水。不良事件的独立预测因素包括患者年龄、就诊年份、社会经济状况、医院特征和伴随的神经系统疾病。2009 年,下尿路症状的急诊就诊总费用为 494981922 美元。

结论

到急诊部就诊的下尿路症状男性数量保持稳定,而急诊就诊费用增加了 40%。研究期间不良事件的发生率有所增加。这些发现可能表明,在当代社会过度依赖医疗和保守治疗。

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